Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice
about
Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDECThe adipocyte-expressed forkhead transcription factor Foxc2 regulates metabolism through altered mitochondrial functionFatty acid metabolism and the basis of brown adipose tissue functionLipid droplet-associated proteins in alcoholic liver disease: a potential linkage with hepatocellular damageLipid droplets as fat storage organelles in Caenorhabditis elegans: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to ManA role for phosphatidic acid in the formation of "supersized" lipid dropletsPerilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytesPackaging of fat: an evolving model of lipid droplet assembly and expansionBrown adipose tissue: Recent insights into development, metabolic function and therapeutic potentialPostlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes.Long-term live cell microscopy studies of lipid droplet fusion dynamics in adipocytes.Regulation of gene expression by FSP27 in white and brown adipose tissue.Cidea control of lipid storage and secretion in mouse and human sebaceous glands.TRPV1 activation counters diet-induced obesity through sirtuin-1 activation and PRDM-16 deacetylation in brown adipose tissue.UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity.Fat-specific protein 27 inhibits lipolysis by facilitating the inhibitory effect of transcription factor Egr1 on transcription of adipose triglyceride lipase.Fat-specific protein 27 undergoes ubiquitin-dependent degradation regulated by triacylglycerol synthesis and lipid droplet formation.Perilipin overexpression in white adipose tissue induces a brown fat-like phenotype.Cideb facilitates the lipidation of chylomicrons in the small intestine.CIDE gene expression in adipose tissue, liver, and skeletal muscle from obese and lean pigsNull mutation in hormone-sensitive lipase gene and risk of type 2 diabetes.Differential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes.The role of lipid droplets in metabolic disease in rodents and humans.KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression.FSP27 promotes lipid droplet clustering and then fusion to regulate triglyceride accumulation.Structural and biochemical characteristics of various white adipose tissue depots.Adaptive thermogenesis in adipocytes: is beige the new brown?Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.Myeloperoxidase deletion prevents high-fat diet-induced obesity and insulin resistance.Regulation of FSP27 protein stability by AMPK and HSC70.Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory responseTwo different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage.Plin2 inhibits cellular glucose uptake through interactions with SNAP23, a SNARE complex proteinAdipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice.Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27.Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis.Defective differentiation of adipose precursor cells from lipodystrophic mice lacking perilipin 1.Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytesInsulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice.CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis.
P2860
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P2860
Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@ast
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@en
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@nl
type
label
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@ast
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@en
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@nl
prefLabel
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@ast
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@en
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@nl
P2093
P2860
P50
P3181
P1433
P1476
Up-regulation of mitochondrial ...... tissue of fsp27 deficient mice
@en
P2093
Huilan Yao
Jingyi Gong
John Zhong Li
Shuqun Yang
P2860
P3181
P356
10.1371/JOURNAL.PONE.0002890
P407
P577
2008-01-01T00:00:00Z