Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis.
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Animal Models of Alcoholic Liver Disease: Pathogenesis and Clinical RelevanceAdipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice.CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis.Possible Involvement of Hepatitis B Virus Infection of Hepatocytes in the Attenuation of Apoptosis in Hepatic Stellate CellsFat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans.Modulation Effect of Peroxisome Proliferator-Activated Receptor Agonists on Lipid Droplet Proteins in Liver.Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes.β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H.CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysisTherapeutic silencing of fat-specific protein 27 improves glycemic control in mouse models of obesity and insulin resistance.Loss of Transcription Factor CREBH Accelerates Diet-Induced Atherosclerosis in Ldlr-/- Mice.Shp deletion prevents hepatic steatosis and when combined with Fxr loss protects against type 2 diabetes.Alcohol and fat promote steatohepatitis: a critical role for fat-specific protein 27/CIDEC.Lipid droplets and liver disease: from basic biology to clinical implications.Negatively-charged residues in the polar carboxy-terminal region in FSP27 are indispensable for expanding lipid droplets.Gut microbiota directs PPARγ-driven reprogramming of the liver circadian clock by nutritional challengePhysiological/pathological ramifications of transcription factors in the unfolded protein response.CIDE Family-Mediated Unique Lipid Droplet Morphology in White Adipose Tissue and Brown Adipose Tissue Determines the Adipocyte Energy Metabolism.Amelioration of diet-induced steatohepatitis in mice following combined therapy with ASO-Fsp27 and fenofibrate.Cell death-inducing DNA fragmentation factor A-like effector A and fat-specific protein 27β coordinately control lipid droplet size in brown adipocytes.A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis.Inflammation is independent of steatosis in a murine model of steatohepatitis.Hairy and enhancer of split 6 prevents hepatic lipid accumulation through inhibition of Pparg2 expression.Improved oxygenation dramatically alters metabolism and gene expression in cultured primary mouse hepatocytes.CREBH Regulates Systemic Glucose and Lipid Metabolism.
P2860
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P2860
Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis.
description
2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Transcriptional activation of ...... growth and hepatic steatosis.
@ast
Transcriptional activation of ...... growth and hepatic steatosis.
@en
type
label
Transcriptional activation of ...... growth and hepatic steatosis.
@ast
Transcriptional activation of ...... growth and hepatic steatosis.
@en
prefLabel
Transcriptional activation of ...... growth and hepatic steatosis.
@ast
Transcriptional activation of ...... growth and hepatic steatosis.
@en
P2093
P2860
P356
P1433
P1476
Transcriptional activation of ...... growth and hepatic steatosis.
@en
P2093
Ann-Hwee Lee
Jae-Seon So
Jong-Gil Park
P2860
P304
P356
10.1002/HEP.27371
P407
P577
2015-01-28T00:00:00Z