Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models
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The Role of Amyloid-β Oligomers in Toxicity, Propagation, and ImmunotherapyNew Features about Tau Function and DysfunctionMisframed ubiquitin and impaired protein quality control: an early event in Alzheimer's diseaseTau Biology and Tau-Directed Therapies for Alzheimer's DiseaseFriend or foe: the dichotomous impact of T cells on neuro-de/re-generation during agingHumanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potencyOligomeric tau-targeted immunotherapy in Tg4510 mice.Passive Immunization in JNPL3 Transgenic Mice Using an Array of Phospho-Tau Specific Antibodies.Naturally Occurring Autoantibodies against Tau Protein Are Reduced in Parkinson's Disease Dementia.Immunotherapeutic Approaches Targeting Amyloid-β, α-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders.Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules.Tau passive immunization inhibits not only tau but also Aβ pathologyCytosolic Fc receptor TRIM21 inhibits seeded tau aggregation.Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope.Promising Targets for the Treatment of Neurodegenerative Diseases.Tau Immunotherapy.Alzheimer Disease: Scientific Breakthroughs and Translational Challenges.Immunotherapies for neurodegenerative diseases: current status and potential of plant-made biopharmaceuticals.Propagation of Tau aggregates.AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy.Internalization of tau antibody and pathological tau protein detected with a flow cytometry multiplexing approachNPT088 reduces both amyloid-β and tau pathologies in transgenic miceEmerging Diagnostic and Therapeutic Strategies for Tauopathies.Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines.Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study.What is the evidence that tau pathology spreads through prion-like propagation?Tauopathies: Mechanisms and Therapeutic Strategies.Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice.Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice.Prospects for strain-specific immunotherapy in Alzheimer's disease and tauopathies.Targeting microglia for the treatment of Alzheimer's Disease.Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.Highly specific and selective anti-pS396-tau antibody C10.2 targets seeding-competent tauAnti-tau conformational scFv MC1 antibody efficiently reduces pathological tau species in adult JNPL3 mice
P2860
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P2860
Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Passive immunization with phos ...... istinct mouse tauopathy models
@ast
Passive immunization with phos ...... istinct mouse tauopathy models
@en
Passive immunization with phos ...... istinct mouse tauopathy models
@nl
type
label
Passive immunization with phos ...... istinct mouse tauopathy models
@ast
Passive immunization with phos ...... istinct mouse tauopathy models
@en
Passive immunization with phos ...... istinct mouse tauopathy models
@nl
prefLabel
Passive immunization with phos ...... istinct mouse tauopathy models
@ast
Passive immunization with phos ...... istinct mouse tauopathy models
@en
Passive immunization with phos ...... istinct mouse tauopathy models
@nl
P2093
P2860
P921
P3181
P1433
P1476
Passive immunization with phos ...... istinct mouse tauopathy models
@en
P2093
Angela Cacace
Bradley Snyder
Charles F Albright
Craig Polson
Donna M Barten
Gregg Hirschfeld
Gregory Cadelina
Jere Meredith
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0125614
P407
P577
2015-01-01T00:00:00Z