Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice.

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Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice.Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.

P2860

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Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice.

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http://www.wikidata.org/entity/Q50045202

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Prophylactic Active Tau Immuni ...... id-β Pathologies in 3xTg Mice.

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Prophylactic Active Tau Immuni ...... id-β Pathologies in 3xTg Mice.

@nl

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Item

label

Prophylactic Active Tau Immuni ...... id-β Pathologies in 3xTg Mice.

@en

Prophylactic Active Tau Immuni ...... id-β Pathologies in 3xTg Mice.

@nl

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Prophylactic Active Tau Immuni ...... id-β Pathologies in 3xTg Mice.

@en

Prophylactic Active Tau Immuni ...... id-β Pathologies in 3xTg Mice.

@nl

P1476

Prophylactic Active Tau Immuni ...... id-β Pathologies in 3xTg Mice.

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P2093

Hameetha Rajamohamedsait

http://www.w3.org/2001/XMLSchema#string

Suhail Rasool

http://www.w3.org/2001/XMLSchema#string

Wajitha Rajamohamedsait

http://www.w3.org/2001/XMLSchema#string

Yan Lin

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P2860

The amyloid hypothesis of Alzheimer's disease at 25 years

Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy.

Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice.

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis.

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

Antibody-derived in vivo imaging of tau pathology.

Tau passive immunotherapy in mutant P301L mice: antibody affinity versus specificity

P304

17034

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scholarly article

P356

10.1038/S41598-017-17313-1

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P407

English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Einar M Sigurdsson

P577

2017-12-06T00:00:00Z

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P698

29213096

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P921

immunization

P932

5719023

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Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice.

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P2860

P2860

Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice.

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type

label

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932