Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex - Wikidata - awgldk - TriplyDB

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex

http://www.wikidata.org/entity/Q27313360

about

Autophagy in malignant transformation and cancer progression Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.The role of oxidative stress and autophagy in atherosclerosis A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance.Dynamins and BAR Proteins-Safeguards against Cancer.The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists.Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology Bcl-xL Affects Group A Streptococcus-Induced Autophagy Directly, by Inhibiting Fusion between Autophagosomes and Lysosomes, and Indirectly, by Inhibiting Bacterial Internalization via Interaction with Beclin 1-UVRAG.BECLIN 1-VPS34 COMPLEX ARCHITECTURE: UNDERSTANDING THE NUTS AND BOLTS OF THERAPEUTIC TARGETS.Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5.Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.Emerging nexus between RAB GTPases, autophagy and neurodegeneration.Knockdown of autophagy-related protein 6, Beclin-1, decreases cell growth, invasion, and metastasis and has a positive effect on chemotherapy-induced cytotoxicity in osteosarcoma cells.An autophagy-independent function for Beclin 1 in cancer.BECN1/Beclin 1 sorts cell-surface APP/amyloid β precursor protein for lysosomal degradation Distinct Rab7-related Endosomal-Autophagic-Lysosomal Dysregulation Observed in Cortex and Hippocampus in APPswe/PSEN1dE9 Mouse Model of Alzheimer's Disease.NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models.Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury.Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice The Mitochondrion-lysosome Axis in Adaptive and Innate Immunity: Effect of Lupus Regulator Peptide P140 on Mitochondria Autophagy and NETosis

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Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex

http://www.wikidata.org/entity/Q27313360

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@ast

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@en

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@nl

type

label

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@ast

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@en

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@nl

prefLabel

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@ast

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@en

Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@nl

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JOURNAL.PGEN.1004626

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Beclin 1 is required for neuro ...... ys via the UVRAG-VPS34 complex

@en

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Greg R Phillips

http://www.w3.org/2001/XMLSchema#string

Mitchell S Wold

http://www.w3.org/2001/XMLSchema#string

Nathaniel Heintz

http://www.w3.org/2001/XMLSchema#string

Nicole C McKnight

http://www.w3.org/2001/XMLSchema#string

Shiaoching Gong

http://www.w3.org/2001/XMLSchema#string

Wei-Xing Zong

http://www.w3.org/2001/XMLSchema#string

Yun Zhong

http://www.w3.org/2001/XMLSchema#string

Zhenyu Yue

http://www.w3.org/2001/XMLSchema#string

Zhixun Dou

http://www.w3.org/2001/XMLSchema#string

P2860

Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking

Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs

A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

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e1004626

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scholarly article

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10.1371/JOURNAL.PGEN.1004626

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10

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10

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2014-10-02T00:00:00Z

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266572013

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25275521

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4183436

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