Tetherin restricts productive HIV-1 cell-to-cell transmission - Wikidata - awgldk - TriplyDB

Tetherin restricts productive HIV-1 cell-to-cell transmission

Tetherin restricts productive HIV-1 cell-to-cell transmission

http://www.wikidata.org/entity/Q27314339

about

Cell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factors HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms BST-2/tetherin: a new component of the innate immune response to enveloped viruses Antiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteraction The role of BST-2/Tetherin in host protection and disease manifestation Vpu Protein: The Viroporin Encoded by HIV-1 HIV restriction in quiescent CD4⁺ T cells Three-Dimensional Structural Characterization of HIV-1 Tethered to Human Cells.Elimination of HIV-1-infected cells by broadly neutralizing antibodies Interferon-induced tetherin restricts vesicular stomatitis virus release in neurons HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway Counteraction of the multifunctional restriction factor tetherin Vpu and BST2: Still Not There Yet?The HIV-1 Vpu viroporin inhibitor BIT225 does not affect Vpu-mediated tetherin antagonism Differential sensitivities of tetherin isoforms to counteraction by primate lentiviruses.Tetherin/BST-2: Restriction Factor or Immunomodulator?Modulation of HIV-1-host interaction: role of the Vpu accessory protein Tetherin restricts direct cell-to-cell infection of HIV-1.HIV-1 Gag, Envelope, and Extracellular Determinants Cooperate To Regulate the Stability and Turnover of Virological Synapses.Tetherin Inhibits Cell-Free Virus Dissemination and Retards Murine Leukemia Virus Pathogenesis Tetherin can restrict cell-free and cell-cell transmission of HIV from primary macrophages to T cells.Contrasting roles for TLR ligands in HIV-1 pathogenesis.HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells.Mouse knockout models for HIV-1 restriction factors.Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo.A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction.Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells.Hyperthermia stimulates HIV-1 replication Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV.Assembly and replication of HIV-1 in T cells with low levels of phosphatidylinositol-(4,5)-bisphosphate.Ex vivo gene therapy for HIV-1 treatment.Pulsed stable isotope labeling of amino acids in cell culture uncovers the dynamic interactions between HIV-1 and the monocyte-derived macrophage.Feline tetherin efficiently restricts release of feline immunodeficiency virus but not spreading of infection.In COS cells Vpu can both stabilize tetherin expression and counteract its antiviral activity.Antibody-mediated enhancement of HIV-1 and HIV-2 production from BST-2/tetherin-positive cells.Structural Basis for the Antiviral Activity of BST-2/Tetherin and Its Viral Antagonism Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells.Innate immunity in acute HIV-1 infection Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo.

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Tetherin restricts productive HIV-1 cell-to-cell transmission

http://www.wikidata.org/entity/Q27314339

description

2010 nî lūn-bûn

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2010 թուականին հրատարակուած գիտական յօդուած

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2010 թվականին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

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name

Tetherin restricts productive HIV-1 cell-to-cell transmission

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Tetherin restricts productive HIV-1 cell-to-cell transmission

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Tetherin restricts productive HIV-1 cell-to-cell transmission

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type

label

Tetherin restricts productive HIV-1 cell-to-cell transmission

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Tetherin restricts productive HIV-1 cell-to-cell transmission

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Tetherin restricts productive HIV-1 cell-to-cell transmission

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prefLabel

Tetherin restricts productive HIV-1 cell-to-cell transmission

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Tetherin restricts productive HIV-1 cell-to-cell transmission

@en

Tetherin restricts productive HIV-1 cell-to-cell transmission

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JOURNAL.PPAT.1000955

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P1476

Tetherin restricts productive HIV-1 cell-to-cell transmission

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Adeline Mallet

http://www.w3.org/2001/XMLSchema#string

Anne-Geneviève Marcelin

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Jerome Feldmann

http://www.w3.org/2001/XMLSchema#string

John Guatelli

http://www.w3.org/2001/XMLSchema#string

P2860

HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation

The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu

Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

Avoiding the void: cell-to-cell spread of human viruses

HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes

Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin

A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells

Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism

HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes

Inhibition of Lassa and Marburg virus production by tetherin

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e1000955

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scholarly article

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650700

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10.1371/JOURNAL.PPAT.1000955

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6

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6

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Marion Sourisseau

Florence Guivel-Benhassine

Nicoletta Casartelli

Anne-Geneviève Marcelin

Olivier Schwartz

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2010-01-01T00:00:00Z

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44807256

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20585562

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HIV transmission

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2887479

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