Glycine receptor mechanism elucidated by electron cryo-microscopy. - Wikidata - awgldk - TriplyDB

Glycine receptor mechanism elucidated by electron cryo-microscopy.

Glycine receptor mechanism elucidated by electron cryo-microscopy.

http://www.wikidata.org/entity/Q27316064

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The Intracellular Loop of the Glycine Receptor: It's not all about the Size Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process.X-ray structure of the human α4β2 nicotinic receptor Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues Resolution advances in cryo-EM enable application to drug discovery.Voltage-Dependent Inhibition of Glycine Receptor Channels by Niflumic Acid Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.Identification of a pre-active conformation of a pentameric channel receptor A Fast and Effective Microfluidic Spraying-Plunging Method for High-Resolution Single-Particle Cryo-EM.Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors.Pentameric quaternary structure of the intracellular domain of serotonin type 3A receptors.Emamectin is a non-selective allosteric activator of nicotinic acetylcholine receptors and GABAA/C receptors.Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor.The development of cryo-EM into a mainstream structural biology technique Functional modulation of glycine receptors by the alkaloid gelsemine.Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel.Investigating the Mechanism by Which Gain-of-function Mutations to the α1 Glycine Receptor Cause Hyperekplexia.Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels Competitive antagonists facilitate the recovery from desensitization of α1β2γ2 GABAA receptors expressed in Xenopus oocytes Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamer Unravelling biological macromolecules with cryo-electron microscopy.Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine Functional Annotation of Ion Channel Structures by Molecular Simulation.Activation-Dependent Rapid Postsynaptic Clustering of Glycine Receptors in Mature Spinal Cord Neurons.Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome.Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel.A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.Acetylcholine nicotinic receptor subtypes in chromaffin cells.Structural Studies of Nicotinic Acetylcholine Receptors: Using Acetylcholine-Binding Protein as a Structural Surrogate.Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease.Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor.Understanding structure-function relationships of the human neuronal acetylcholine receptor: insights from the first crystal structures of neuronal subunits.Structural mechanisms of activation and desensitization in neurotransmitter-gated ion channels.Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.Direct interaction of the resistance to inhibitors of cholinesterase type 3 protein with the serotonin receptor type 3A intracellular domain.Detergents: Friends not foes for high-performance membrane proteomics toward precision medicine.

P2860

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P2860

Glycine receptor mechanism elucidated by electron cryo-microscopy.

http://www.wikidata.org/entity/Q27316064

description

2015 nî lūn-bûn

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2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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name

Glycine receptor mechanism elucidated by electron cryo-microscopy

@nl

Glycine receptor mechanism elucidated by electron cryo-microscopy.

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Glycine receptor mechanism elucidated by electron cryo-microscopy.

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type

label

Glycine receptor mechanism elucidated by electron cryo-microscopy

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Glycine receptor mechanism elucidated by electron cryo-microscopy.

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Glycine receptor mechanism elucidated by electron cryo-microscopy.

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prefLabel

Glycine receptor mechanism elucidated by electron cryo-microscopy

@nl

Glycine receptor mechanism elucidated by electron cryo-microscopy.

@ast

Glycine receptor mechanism elucidated by electron cryo-microscopy.

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Glycine receptor mechanism elucidated by electron cryo-microscopy.

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P2093

Eric Gouaux

http://www.w3.org/2001/XMLSchema#string

Juan Du

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Shenping Wu

http://www.w3.org/2001/XMLSchema#string

Wei Lü

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Yifan Cheng

http://www.w3.org/2001/XMLSchema#string

P2860

A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors

The beta subunit determines the ligand binding properties of synaptic glycine receptors

MolProbity: all-atom structure validation for macromolecular crystallography

The impact of human hyperekplexia mutations on glycine receptor structure and function

Structure and gating mechanism of the acetylcholine receptor pore

Crystal structure of a human GABAA receptor

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

Principles of activation and permeation in an anion-selective Cys-loop receptor

Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines

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224-229

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10.1038/NATURE14853

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526

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2015-09-07T00:00:00Z

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1039215522

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26344198

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cryogenic electron microscopy

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4659708

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