Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1 - Wikidata - awgldk - TriplyDB

Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

http://www.wikidata.org/entity/Q27322213

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Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells Role of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer's Disease and Spinal Cord Injury A dynamic interface between ubiquitylation and cAMP signaling Mitochondrial morphology-emerging role in bioenergetics Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease Mitochondrial fission: regulation and ER connection Role of protein kinase A in regulating mitochondrial function and neuronal development: implications to neurodegenerative diseases Dynamin-related protein 1 controls the migration and neuronal differentiation of subventricular zone-derived neural progenitor cells Mitochondrial cAMP signaling Mitochondrial dynamics and viral infections: A close nexus Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes Interaction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteins Tau promotes neurodegeneration via DRP1 mislocalization in vivo Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules.A calcineurin docking motif (LXVP) in dynamin-related protein 1 contributes to mitochondrial fragmentation and ischemic neuronal injury.The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons.Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians.Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.Pseudoscaffolds and anchoring proteins: the difference is in the details.Pericellular pH homeostasis is a primary function of the Warburg effect: inversion of metabolic systems to control lactate steady state in tumor cells.Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission Mechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acid Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A Mitochondrial fusion is essential for steroid biosynthesis GSK3beta-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress.Bcl-xL is necessary for neurite outgrowth in hippocampal neurons Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.Activation of the pleiotropic drug resistance pathway can promote mitochondrial DNA retention by fusion-defective mitochondria in Saccharomyces cerevisiae.Neural activity and CaMKII protect mitochondria from fragmentation in aging Caenorhabditis elegans neurons.Allosteric modulation of Drp1 mechanoenzyme assembly and mitochondrial fission by the variable domain.Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans.N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival.Ketamine enhances human neural stem cell proliferation and induces neuronal apoptosis via reactive oxygen species-mediated mitochondrial pathway Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention.Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration.PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy.

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

http://www.wikidata.org/entity/Q27322213

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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type

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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prefLabel

Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

@ast

Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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JOURNAL.PBIO.1000612

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Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1

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J Thomas Cribbs

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Steven H Green

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling

The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

G domain dimerization controls dynamin's assembly-stimulated GTPase activity

A system for stable expression of short interfering RNAs in mammalian cells

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

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10.1371/JOURNAL.PBIO.1000612

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Audrey S Dickey

Yuriy M Usachev

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51082834

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21526220

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