Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer
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MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signalingPromising Therapy Candidates for Liver FibrosisHCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2Stem-like plasticity and heterogeneity of circulating tumor cells: current status and prospect challenges in liver cancerMembrane-to-Nucleus Signals and Epigenetic Mechanisms for Myofibroblastic Activation and Desmoplastic Stroma: Potential Therapeutic Targets for Liver Metastasis?Potential role of Hedgehog pathway in liver response to radiationEvolving therapies for liver fibrosis.Hedgehog signaling pathway mediates invasion and metastasis of hepatocellular carcinoma via ERK pathway.Hedgehog inhibition reduces angiogenesis by downregulation of tumoral VEGF-A expression in hepatocellular carcinoma.Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis.Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.Fibrosis-dependent mechanisms of hepatocarcinogenesisRole of liver stem cells in hepatocarcinogenesis.Principles of liver regeneration and growth homeostasis.Great challenges in molecular medicine: toward personalized medicine.Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis.Interleukin-1β attenuates myofibroblast formation and extracellular matrix production in dermal and lung fibroblasts exposed to transforming growth factor-β1Novel insights into the function and dynamics of extracellular matrix in liver fibrosis.Evaluation of 11C-acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma.Inflammatory models drastically alter tumor growth and the immune microenvironment in hepatocellular carcinoma.Hepatitis C virus infection: establishment of chronicity and liver disease progressionReemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications.RNA-sequencing analysis of 5' capped RNAs identifies many new differentially expressed genes in acute hepatitis C virus infectionHedgehog controls hepatic stellate cell fate by regulating metabolismHedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein.Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma.Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation.NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease.Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisationMicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.Smoothened is a master regulator of adult liver repair.Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes.In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.MicroRNA Expression Profiling in CCl₄-Induced Liver Fibrosis of Mus musculus.Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.Crosstalk between TGF-β and hedgehog signaling in cancer.Review article: non-alcoholic fatty liver disease and osteoporosis--clinical and molecular crosstalk.Inhibition of Hedgehog signaling in the gastrointestinal tract: targeting the cancer microenvironment.Desmoplastic stroma and cholangiocarcinoma: clinical implications and therapeutic targeting.
P2860
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P2860
Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Hedgehog signaling antagonist ...... model of primary liver cancer
@ast
Hedgehog signaling antagonist ...... model of primary liver cancer
@en
Hedgehog signaling antagonist ...... model of primary liver cancer
@nl
type
label
Hedgehog signaling antagonist ...... model of primary liver cancer
@ast
Hedgehog signaling antagonist ...... model of primary liver cancer
@en
Hedgehog signaling antagonist ...... model of primary liver cancer
@nl
prefLabel
Hedgehog signaling antagonist ...... model of primary liver cancer
@ast
Hedgehog signaling antagonist ...... model of primary liver cancer
@en
Hedgehog signaling antagonist ...... model of primary liver cancer
@nl
P2093
P2860
P3181
P1433
P1476
Hedgehog signaling antagonist ...... model of primary liver cancer
@en
P2093
Anna Mae Diehl
Christopher Lascola
Cynthia Guy
Cynthia Moylan
Elmar Merkle
Fatima Rangwala
Gamze F Karaca
George M Philips
Isaac S Chan
Marzena Swiderska
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0023943
P407
P577
2011-01-01T00:00:00Z