In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
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Tamoxifen Resistance: Emerging Molecular TargetsThe hedgehog pathway in triple-negative breast cancerIn smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factor.HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.Anti-cancer stem cell activity of a hedgehog inhibitor GANT61 in estrogen receptor-positive breast cancer cells.Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line.In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma.Transcriptome analyses of taste organoids reveal multiple pathways involved in taste cell generation.Smoothened is a poor prognosis factor and a potential therapeutic target in glioma.The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo.Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond.Inhibition of the CyclinD1 promoter in response to sonic hedgehog signaling pathway transduction is mediated by Gli1Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells.Prognostic role of Gli1 expression in breast cancer: a meta-analysis.Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.Nanocarrier based approaches for targeting breast cancer stem cells.Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer.SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer.Glioma-Associated Oncogene Homolog Inhibitors Have the Potential of Suppressing Cancer Stem Cells of Breast Cancer.The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK.Inhibition of the Hedgehog Signaling Pathway Depresses the Cigarette Smoke-Induced Malignant Transformation of 16HBE Cells on a Microfluidic Chip.Role of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic TargetsHedgehog Signaling Pathway and Autophagy in CancerEffect of the BH3 Mimetic Polyphenol (-)-Gossypol (AT-101) on the and Growth of Malignant Mesothelioma
P2860
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P2860
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
In vitro and in vivo inhibitio ...... ) or GLI (GANT-61) inhibitors.
@en
type
label
In vitro and in vivo inhibitio ...... ) or GLI (GANT-61) inhibitors.
@en
prefLabel
In vitro and in vivo inhibitio ...... ) or GLI (GANT-61) inhibitors.
@en
P2093
P2860
P50
P356
P1433
P1476
In vitro and in vivo inhibitio ...... 9) or GLI (GANT-61) inhibitors
@en
P2093
Alberto Gulino
Andrea Modesti
Augusto Orlandi
Danilo Cucchi
Elena Bonanno
Enrica Di Stefano
Giovanni Vanni Frajese
Isabella Screpanti
Laura Masuelli
Roberto Bei
P2860
P304
P356
10.18632/ONCOTARGET.7062
P407
P577
2016-02-01T00:00:00Z