Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores.
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Bacterial Toxins as Pathogen Weapons Against PhagocytesPertussis: Microbiology, Disease, Treatment, and Prevention.Bordetella adenylate cyclase toxin interacts with filamentous haemagglutinin to inhibit biofilm formation in vitro.Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size.Effect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1β production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation.Bordetella pertussis pathogenesis: current and future challenges.A critical role for hemolysin in Vibrio fluvialis-induced IL-1β secretion mediated by the NLRP3 inflammasome in macrophagesAdenylate cyclase toxin-hemolysin relevance for pertussis vaccines.Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme.Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis.The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin.Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity.Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes.Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates.cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity.Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cells.Bordetella pertussis adenylate cyclase toxin disrupts functional integrity of bronchial epithelial layers.Bordetella Pertussis virulence factors in the continuing evolution of whooping cough vaccines for improved performance.Pore-formation by adenylate cyclase toxoid activates dendritic cells to prime CD8+ and CD4+ T cells.cAMP signalling of Bordetella adenylate cyclase toxin through the SHP-1 phosphatase activates the BimEL-Bax pro-apoptotic cascade in phagocytes.Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Adenylyl Cyclase Enzyme Domain.Functional Consequences of Calcium Influx Promoted by Bacterial Pore-Forming Toxins
P2860
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P2860
Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores.
description
2012 nî lūn-bûn
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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Calcium influx rescues adenyla ...... ermeabilization by toxin pores
@nl
Calcium influx rescues adenyla ...... rmeabilization by toxin pores.
@ast
Calcium influx rescues adenyla ...... rmeabilization by toxin pores.
@en
type
label
Calcium influx rescues adenyla ...... ermeabilization by toxin pores
@nl
Calcium influx rescues adenyla ...... rmeabilization by toxin pores.
@ast
Calcium influx rescues adenyla ...... rmeabilization by toxin pores.
@en
prefLabel
Calcium influx rescues adenyla ...... ermeabilization by toxin pores
@nl
Calcium influx rescues adenyla ...... rmeabilization by toxin pores.
@ast
Calcium influx rescues adenyla ...... rmeabilization by toxin pores.
@en
P2093
P2860
P50
P1433
P1476
Calcium influx rescues adenyla ...... rmeabilization by toxin pores.
@en
P2093
Catherine Fayolle
Claude Leclerc
Eva Pospisilova
Irena Adkins
Ivo Konopasek
Jiri Masin
Ladislav Bumba
Lenka Sadilkova
P2860
P304
P356
10.1371/JOURNAL.PPAT.1002580
P407
P577
2012-04-05T00:00:00Z