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The role of animal models for research on severe malaria

The role of animal models for research on severe malaria

http://www.wikidata.org/entity/Q27348351

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Endothelial-Leukocyte Interaction in Severe Malaria: Beyond the Brain Magnetic resonance imaging during life: the key to unlock cerebral malaria pathogenesis?Vascular dysfunction as a target for adjuvant therapy in cerebral malaria The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development.Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis Intravital placenta imaging reveals microcirculatory dynamics impact on sequestration and phagocytosis of Plasmodium-infected erythrocytes Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria Molecular evolution and phylogenetics of rodent malaria parasites A comprehensive evaluation of rodent malaria parasite genomes and gene expression Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria Altered Lipid Composition of Surfactant and Lung Tissue in Murine Experimental Malaria-Associated Acute Respiratory Distress Syndrome The origins of malaria: there are more things in heaven and earth …Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins The Malaria-High Blood Pressure Hypothesis.Effect of mature blood-stage Plasmodium parasite sequestration on pathogen biomass in mathematical and in vivo models of malaria.Simultaneously targeting inflammatory response and parasite sequestration in brain to treat Experimental Cerebral Malaria Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen.Piecing together the puzzle of severe malaria.Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response.IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice.Host-Parasite Interactions in Human Malaria: Clinical Implications of Basic Research Translational Rodent Models for Research on Parasitic Protozoa-A Review of Confounders and Possibilities Lys48 ubiquitination during the intraerythrocytic cycle of the rodent malaria parasite, Plasmodium chabaudi Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease.The role of EPCR in the pathogenesis of severe malaria Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection Metabolomics in the fight against malaria.Loss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria Plasmodium coatneyi in rhesus macaques replicates the multisystemic dysfunction of severe malaria in humans Erythropoietin Combined with Liposomal Amphotericin B Improves Outcome during Disseminated Aspergillosis in Mice Natural transmission of Plasmodium berghei exacerbates chronic tuberculosis in an experimental co-infection model Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria.Investigation of hydrogen sulfide gas as a treatment against P. falciparum, murine cerebral malaria, and the importance of thiolation state in the development of cerebral malaria.Lipoxin A₄ and 15-epi-lipoxin A₄ protect against experimental cerebral malaria by inhibiting IL-12/IFN-γ in the brain Efficacy of intranasal administration of artesunate in experimental cerebral malaria Activated Brain Endothelial Cells Cross-Present Malaria Antigen Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria.Experimental Models of Microvascular Immunopathology: The Example of Cerebral Malaria.

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The role of animal models for research on severe malaria

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The role of animal models for research on severe malaria

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Molecular interactions in the placenta during malaria infection

Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA

Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2

Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes

alpha-Tocopherol transfer protein inhibition is effective in the prevention of cerebral malaria in mice

Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study

Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study

Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster

Clinical and Laboratory Features of HumanPlasmodium knowlesiInfection

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