Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer
about
Bcl-2 family proteins as regulators of cancer cell invasion and metastasis: a review focusing on mitochondrial respiration and reactive oxygen speciesSevere lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44.Bcl-xL promotes metastasis independent of its anti-apoptotic activity.The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria.Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli.Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.BCL-XL overexpression promotes tumor progression-associated properties.
P2860
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P2860
Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer
description
2009 nî lūn-bûn
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2009 թուականին հրատարակուած գիտական յօդուած
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2009 թվականին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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name
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@ast
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@en
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@nl
type
label
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@ast
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@en
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@nl
prefLabel
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@ast
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@en
Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@nl
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P2860
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Genetic ablation of Bcl-x atte ...... ncreatic neuroendocrine cancer
@en
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Danielle B Ulanet
Douglas Hanahan
Jeffrey H Hager
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P3181
P356
10.1371/JOURNAL.PONE.0004455
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P577
2009-01-01T00:00:00Z