Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1
about
Biological Transmission of Arboviruses: Reexamination of and New Insights into Components, Mechanisms, and Unique Traits as Well as Their Evolutionary TrendsDominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activityInterplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virusMx1-based resistance to thogoto virus in A2G mice is bypassed in tick-mediated virus deliveryHuman MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infectionsHuman MxA protein confers resistance to Semliki Forest virus and inhibits the amplification of a Semliki Forest virus-based replicon in the absence of viral structural proteinsNovel gene product of Thogoto virus segment 6 codes for an interferon antagonist.Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virusNucleoprotein viral RNA and mRNA of Thogoto virus: a novel "cap-stealing" mechanism in tick-borne orthomyxoviruses?The 5' ends of Thogoto virus (Orthomyxoviridae) mRNAs are homogeneous in both length and sequenceIn vitro polymerase activity of Thogoto virus: evidence for a unique cap-snatching mechanism in a tick-borne orthomyxovirusInterferon-inducible antiviral effectorsIn vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein.Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assemblyInterferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses.Herpes simplex virus-1 induces expression of a novel MxA isoform that enhances viral replication.Production of transgenic pigs over-expressing the antiviral gene Mx1.Enhanced virus resistance of transgenic mice expressing the human MxA protein.Cloning of the rainbow trout (Oncorhynchus mykiss) Mx2 and Mx3 cDNAs and characterization of trout Mx protein expression in salmon cells.Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.Antiviral determinants of rat Mx GTPases map to the carboxy-terminal half.Influenza Virus Susceptibility of Wild-Derived CAST/EiJ Mice Results from Two Amino Acid Changes in the MX1 Restriction Factor.A genetic model of differential susceptibility to human respiratory syncytial virus (RSV) infection.Mx proteins: antiviral gatekeepers that restrain the uninvited.Tick-Borne Viruses and Biological Processes at the Tick-Host-Virus Interface.Evolution and Antiviral Specificities of Interferon-Induced Mx Proteins of Bats against Ebola, Influenza, and Other RNA Viruses.In Vivo Conditions Enable IFNAR-Independent Type I Interferon Production by Peritoneal CD11b+ Cells upon Thogoto Virus Infection.The interferon antagonist ML protein of thogoto virus targets general transcription factor IIB.Thogoto virus lacking interferon-antagonistic protein ML is strongly attenuated in newborn Mx1-positive but not Mx1-negative mice.Structural requirements for the antiviral activity of the human MxA protein against Thogoto and influenza A virusThogoto virus infection induces sustained type I interferon responses that depend on RIG-I-like helicase signaling of conventional dendritic cells
P2860
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P2860
Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@ast
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@en
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@nl
type
label
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@ast
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@en
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@nl
prefLabel
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@ast
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@en
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@nl
P2093
P2860
P1433
P1476
Tick-borne thogoto virus infec ...... us resistance gene product Mx1
@en
P2093
P2860
P304
P50
P577
1995-04-01T00:00:00Z