Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation
about
Molecular targets for flavivirus drug discoveryComparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemicCharacterization of defective viral RNA produced during persistent infection of Vero cells with Murray Valley encephalitis virustrans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells.Antiapoptotic but not antiviral function of human bcl-2 assists establishment of Japanese encephalitis virus persistence in cultured cellsAttenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3cis- and trans-acting elements in flavivirus RNA replicationGenetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function.Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashionEfficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicasePurification and Characterization of West Nile Virus Nucleoside Triphosphatase (NTPase)/Helicase: Evidence for Dissociation of the NTPase and Helicase Activities of the EnzymeMutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication.Salicylates inhibit flavivirus replication independently of blocking nuclear factor kappa B activation.The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity.NS1 protein secretion during the acute phase of West Nile virus infectionDerivation and characterization of a dengue type 1 host range-restricted mutant virus that is attenuated and highly immunogenic in monkeys.Antiviral effects of an iminosugar derivative on flavivirus infectionsPaired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes.Flavivirus nonstructural protein NS1: Complementary surprisesUltrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structurestrans-Complementation of yellow fever virus NS1 reveals a role in early RNA replicationUse of a commercial enzyme immunoassay to monitor dengue virus replication in cultured cellsConstruction of an infectious cDNA clone for a Brazilian prototype strain of dengue virus type 1: Characterization of a temperature-sensitive mutation in NS1MKRN1 Induces Degradation of West Nile Virus Capsid Protein by Functioning as an E3 LigaseAbrogation of TLR3 inhibition by discrete amino acid changes in the C-terminal half of the West Nile virus NS1 protein.Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5.The flavivirus protease as a target for drug discovery.Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein.Charged residues in hepatitis C virus NS4B are critical for multiple NS4B functions in RNA replication.Flavivirus RNA cap methyltransferase: structure, function, and inhibition.Structure and function of the 3' terminal six nucleotides of the west nile virus genome in viral replication.North American West Nile virus genotype isolates demonstrate differential replicative capacities in response to temperature.Replication cycle and molecular biology of the West Nile virus.Population structure of the dengue viruses, Aragua, Venezuela, 2006-2007. Insights into dengue evolution under hyperendemic transmission.Molecular Docking Based Screening of Plant Flavonoids as Dengue NS1 Inhibitors.Development of a quantitative NS1-capture enzyme-linked immunosorbent assay for early detection of yellow fever virus infection.African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo.Biochemistry and Molecular Biology of Flaviviruses.
P2860
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P2860
Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Genetic analysis of the yellow ...... which blocks RNA accumulation
@ast
Genetic analysis of the yellow ...... which blocks RNA accumulation
@en
Genetic analysis of the yellow ...... which blocks RNA accumulation
@nl
type
label
Genetic analysis of the yellow ...... which blocks RNA accumulation
@ast
Genetic analysis of the yellow ...... which blocks RNA accumulation
@en
Genetic analysis of the yellow ...... which blocks RNA accumulation
@nl
prefLabel
Genetic analysis of the yellow ...... which blocks RNA accumulation
@ast
Genetic analysis of the yellow ...... which blocks RNA accumulation
@en
Genetic analysis of the yellow ...... which blocks RNA accumulation
@nl
P2093
P2860
P1433
P1476
Genetic analysis of the yellow ...... which blocks RNA accumulation
@en
P2093
P2860
P304
P577
1997-01-01T00:00:00Z