Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein
about
The role of innate versus adaptive immune responses in a mouse model of O'nyong-nyong virus infectionChikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signalingMutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2Alphavirus RNA synthesis and non-structural protein functionsDifferences in Processing Determinants of Nonstructural Polyprotein and in the Sequence of Nonstructural Protein 3 Affect Neurovirulence of Semliki Forest VirusThe role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses.Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design.Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence DeterminantsAn alphavirus-based adjuvant enhances serum and mucosal antibodies, T cells, and protective immunity to influenza virus in neonatal miceEncapsidation of host-derived factors correlates with enhanced infectivity of Sindbis virusIdentification and characterization of a ross river virus variant that grows persistently in macrophages, shows altered disease kinetics in a mouse model, and exhibits resistance to type I interferonNoncapped Alphavirus Genomic RNAs and Their Role during Infection.An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivoBoth RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode.Mechanism of action of mRNA-based vaccines.Molecular mechanisms involved in the pathogenesis of alphavirus-induced arthritis.A determinant of Sindbis virus neurovirulence enables efficient disruption of Jak/STAT signaling.Early events in alphavirus replication determine the outcome of infection.Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology.Recombinant Vaccinia virus-coded interferon inhibitor B18R: Expression, refolding and a use in a mammalian expression system with a RNA-vector.Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs
P2860
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P2860
Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@ast
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@en
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@nl
type
label
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@ast
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@en
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@nl
prefLabel
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@ast
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@en
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@nl
P2093
P2860
P1433
P1476
Modulation of type I IFN induc ...... in the alphavirus nsP1 protein
@en
P2093
Catherine C Cruz
Jason Simmons
Mehul S Suthar
Robert E Johnston
Stephanie A Montgomery
Thomas E Morrison
P2860
P356
10.1016/J.VIROL.2009.12.031
P407
P577
2010-03-30T00:00:00Z