Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs
about
Prediction of co-receptor usage of HIV-1 from genotypeHIV-1 envelope glycoprotein structureComputational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.Plasticity in protein-peptide recognition: crystal structures of two different peptides bound to concanavalin A.Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 NeutralizationStructure determination of an anti-HIV-1 Fab 447-52D–peptide complex from an epitaxially twinned data setA Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing AntibodiesNoncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088Crystal Structure of the HIV-2 Neutralizing Fab Fragment 7C8 with High Specificity to the V3 Region of gp125Structure of an Antibody in Complex with Its Mucin Domain Linear Epitope That Is Protective against Ebola VirusRabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected HumansCrystal Structure of a Soluble Cleaved HIV-1 Envelope TrimerDiscrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralizationAntibody modeling assessment II. Structures and modelsStructure-Based Reverse Vaccinology Failed in the Case of HIV Because it Disregarded Accepted Immunological TheoryCorrelation between conformation and antibody binding: NMR structure of cross-reactive peptides from T. cruzi, human and L. braziliensisMax Bergmann lecture protein epitope mimetics in the age of structural vaccinology3D structure model of the principal neutralizing epitope of Minnesota HIV-1 isolate.Dual spatial folds and different local structures of the HIV-1 immunogenic crown in various virus isolates.Conformational preferences of the HIV-1 principal neutralizing determinant.Structural analysis of the HIV-1 gp120 V3 loop: application to the HIV-Haiti isolates.Conformational model for the consensus V3 loop of the envelope protein gp120 of HIV-1 in a 20% trifluoroethanol/water solution.Protein intrinsic disorder toolbox for comparative analysis of viral proteins.Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus.Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades.Requirements for empirical immunogenicity trials, rather than structure-based design, for developing an effective HIV vaccine.Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations.Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 bindingNucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.Analysis and modeling of the variable region of camelid single-domain antibodies.Structure and immune recognition of trimeric pre-fusion HIV-1 Env.Intraprotomer masking of third variable loop (V3) epitopes by the first and second variable loops (V1V2) within the native HIV-1 envelope glycoprotein trimer.Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8.Human immunodeficiency virus-1 gp120 V3 loop for anti-acquired immune deficiency syndrome drug discovery: computer-aided approaches to the problem solving.A model of a gp120 V3 peptide in complex with an HIV-neutralizing antibody based on NMR and mutant cycle-derived constraints.Structural and thermodynamic insights into the recognition of native proteins by anti-peptide antibodies.Distinct mechanisms regulate exposure of neutralizing epitopes in the V2 and V3 loops of HIV-1 envelope.Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination.In vivo CXCR4 expression, lymphoid cell phenotype, and feline immunodeficiency virus infection.Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis.
P2860
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P2860
Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Dual conformations for the HIV ...... th different neutralizing fabs
@ast
Dual conformations for the HIV ...... th different neutralizing fabs
@en
Dual conformations for the HIV ...... th different neutralizing fabs
@nl
type
label
Dual conformations for the HIV ...... th different neutralizing fabs
@ast
Dual conformations for the HIV ...... th different neutralizing fabs
@en
Dual conformations for the HIV ...... th different neutralizing fabs
@nl
prefLabel
Dual conformations for the HIV ...... th different neutralizing fabs
@ast
Dual conformations for the HIV ...... th different neutralizing fabs
@en
Dual conformations for the HIV ...... th different neutralizing fabs
@nl
P2093
P3181
P1433
P1476
Dual conformations for the HIV ...... th different neutralizing fabs
@en
P2093
A Satterthwait
R Stanfield
P304
P3181
P356
10.1016/S0969-2126(99)80020-3
P50
P577
1999-02-15T00:00:00Z