Intraprotomer masking of third variable loop (V3) epitopes by the first and second variable loops (V1V2) within the native HIV-1 envelope glycoprotein trimer.
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Crystal Structure of a Soluble Cleaved HIV-1 Envelope TrimerBioinformatic analysis of HIV-1 entry and pathogenesis.Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivityThe Patterns of Coevolution in Clade B HIV Envelope's N-Glycosylation SitesDynamic electrophoretic fingerprinting of the HIV-1 envelope glycoprotein.Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120Visualization of retroviral envelope spikes in complex with the V3 loop antibody 447-52D on intact viruses by cryo-electron tomography.Analysis of the subunit stoichiometries in viral entry.The presence of glutamine at position 315 but not epitope masking predominantly hinders HIV subtype C neutralization by the anti-V3 antibody B4e8.A small set of succinct signature patterns distinguishes Chinese and non-Chinese HIV-1 genomes.Estimated secondary structure propensities within V1/V2 region of HIV gp120 are an important global antibody neutralization sensitivity determinant.Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor ActivityRationally Targeted Mutations at the V1V2 Domain of the HIV-1 Envelope to Augment Virus Neutralization by Anti-V1V2 Monoclonal Antibodies.Coevolution Analysis of HIV-1 Envelope Glycoprotein Complex.Adenoviral vectors elicit humoral immunity against variable loop 2 of clade C HIV-1 gp120 via "Antigen Capsid-Incorporation" strategy.HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds.Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers.Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein.HIV-1 clade C escapes broadly neutralizing autologous antibodies with N332 glycan specificity by distinct mechanismsTyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry.HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity.Elicitation of broadly reactive antibodies against glycan-modulated neutralizing V3 epitopes of HIV-1 by immune complex vaccines.HIV-1 specific antibody titers and neutralization among chronically infected patients on long-term suppressive antiretroviral therapy (ART): a cross-sectional study.Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivityLoss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits.Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5.Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques.The biological characteristics of predominant strains of HIV-1 genotype: modeling of HIV-1 infection among men who have sex with men.In silico design of novel broad anti-HIV-1 agents based on glycosphingolipid β-galactosylceramide, a high-affinity receptor for the envelope gp120 V3 loop.Discovery of novel anti-HIV-1 agents based on a broadly neutralizing antibody against the envelope gp120 V3 loop: a computational study.HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.
P2860
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P2860
Intraprotomer masking of third variable loop (V3) epitopes by the first and second variable loops (V1V2) within the native HIV-1 envelope glycoprotein trimer.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Intraprotomer masking of third ...... envelope glycoprotein trimer.
@ast
Intraprotomer masking of third ...... envelope glycoprotein trimer.
@en
type
label
Intraprotomer masking of third ...... envelope glycoprotein trimer.
@ast
Intraprotomer masking of third ...... envelope glycoprotein trimer.
@en
prefLabel
Intraprotomer masking of third ...... envelope glycoprotein trimer.
@ast
Intraprotomer masking of third ...... envelope glycoprotein trimer.
@en
P2093
P2860
P356
P1476
Intraprotomer masking of third ...... envelope glycoprotein trimer.
@en
P2093
Edward A Berger
Paolo Lusso
Raffaello Cimbro
P2860
P304
20148-20153
P356
10.1073/PNAS.1104840108
P407
P577
2011-11-29T00:00:00Z