Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase
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The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductasesCrystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysisClass II 3-hydroxy-3-methylglutaryl coenzyme A reductasesCrystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductaseA Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A ReductaseExploration of virtual candidates for human HMG-CoA reductase inhibitors using pharmacophore modeling and molecular dynamics simulationsEnterococcus faecalis phosphomevalonate kinase.Molecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases.An Insight Into Structure, Function, and Expression Analysis of 3-Hydroxy-3-Methylglutaryl-CoA Reductase of Cymbopogon winterianus.Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci.Essentiality, expression, and characterization of the class II 3-hydroxy-3-methylglutaryl coenzyme A reductase of Staphylococcus aureus.Enzymes of the mevalonate pathway of isoprenoid biosynthesisPurification, crystallization and preliminary X-ray analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase of Streptococcus pneumoniae.Regulation of HMG-CoA reductase in mammals and yeastDual coenzyme specificity of Archaeoglobus fulgidus HMG-CoA reductase.Molecular modeling of the reaction pathway and hydride transfer reactions of HMG-CoA reductase.The role of the 3-hydroxy 3-methylglutaryl coenzyme A reductase cytosolic domain in karmellae biogenesis.Isoprenoids in three-dimensional space: the stereochemistry of terpene biosynthesis.The increasingly complex mechanism of HMG-CoA reductase.A critical role of mevalonate for peptidoglycan synthesis in Staphylococcus aureus.Inferring functional constraints and divergence in protein families using 3D mapping of phylogenetic information.Methyl farnesoate synthesis in the lobster mandibular organ: the roles of HMG-CoA reductase and farnesoic acid O-methyltransferaseKinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase.The kinetic mechanism of phosphomevalonate kinase.Improved prediction of protein-protein binding sites using a support vector machines approach.QM/MM study of the mechanism of reduction of 3-hydroxy-3-methylglutaryl coenzyme A catalyzed by human HMG-CoA reductase
P2860
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P2860
Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@ast
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@en
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@nl
type
label
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@ast
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@en
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@nl
prefLabel
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@ast
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@en
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@nl
P2093
P2860
P356
P1476
Substrate-induced closure of t ...... 3-methylglutaryl-CoA reductase
@en
P2093
C V Stauffacher
D A Bochar
L Tabernero
V W Rodwell
P2860
P304
P356
10.1073/PNAS.96.13.7167
P407
P577
1999-06-22T00:00:00Z