Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci.
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The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL1903-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time"Origin and molecular evolution of the determinant of methicillin resistance in staphylococciClass II 3-hydroxy-3-methylglutaryl coenzyme A reductasesMevalonate kinase deficiency: current perspectivesCrystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductaseCrystal structure of theStreptococcus pneumoniaemevalonate kinase in complex with diphosphomevalonateHuman mevalonate diphosphate decarboxylase: Characterization, investigation of the mevalonate diphosphate binding site, and crystal structureSynthesis of CDP-Activated Ribitol for Teichoic Acid Precursors in Streptococcus pneumoniaeStructure of the Ternary Complex of Phosphomevalonate Kinase: The Enzyme and Its FamilyCrystal Structures of Staphylococcus epidermidis Mevalonate Diphosphate Decarboxylase Bound to Inhibitory Analogs Reveal New Insight into Substrate Binding and CatalysisA Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A ReductaseStructural Basis for Nucleotide Binding and Reaction Catalysis in Mevalonate Diphosphate DecarboxylaseKinetics of phosphomevalonate kinase from Saccharomyces cerevisiaeEnterococcus faecalis phosphomevalonate kinase.Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH)Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus.Mevalonate analogues as substrates of enzymes in the isoprenoid biosynthetic pathway of Streptococcus pneumoniae.Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae.Essentiality, expression, and characterization of the class II 3-hydroxy-3-methylglutaryl coenzyme A reductase of Staphylococcus aureus.Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria.Studies on the antibacterial effects of statins--in vitro and in vivo.Functional microdomains in bacterial membranesEnzymes of the mevalonate pathway of isoprenoid biosynthesisLovastatin has significant activity against zygomycetes and interacts synergistically with voriconazole.Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis.Enterococcus faecalis 3-hydroxy-3-methylglutaryl coenzyme A synthase, an enzyme of isopentenyl diphosphate biosynthesis.Structure and biosynthesis of staphyloxanthin from Staphylococcus aureus.From microbial gene essentiality to novel antimicrobial drug targetsOverexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene productionNovel targets for the future development of antibacterial agents.The role of genomics in the discovery of novel targets for antibiotic therapy.Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability.Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylasesThe Putative mevalonate diphosphate decarboxylase from Picrophilus torridus is in reality a mevalonate-3-kinase with high potential for bioproduction of isobuteneExploring the existence of lipid rafts in bacteria.Uncovering major genomic features of essential genes in Bacteria and a methanogenic ArchaeaFunctional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilisSuperessential reactions in metabolic networks
P2860
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P2860
Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci.
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification, evolution, and ...... thesis in gram-positive cocci.
@ast
Identification, evolution, and ...... thesis in gram-positive cocci.
@en
type
label
Identification, evolution, and ...... thesis in gram-positive cocci.
@ast
Identification, evolution, and ...... thesis in gram-positive cocci.
@en
prefLabel
Identification, evolution, and ...... thesis in gram-positive cocci.
@ast
Identification, evolution, and ...... thesis in gram-positive cocci.
@en
P2093
P2860
P1476
Identification, evolution, and ...... thesis in gram-positive cocci.
@en
P2093
A F Chalker
A P Bryant
D J Holmes
E I Wilding
K A Ingraham
M Rosenberg
S Iordanescu
P2860
P304
P356
10.1128/JB.182.15.4319-4327.2000
P407
P577
2000-08-01T00:00:00Z