Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
about
Orexin receptors: pharmacology and therapeutic opportunitiesPhysiology of the orexinergic/hypocretinergic system: a revisit in 2012Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptorsThe SK-N-MC cell line expresses an orexin binding site different from recombinant orexin 1-type receptorNMR conformational studies of micelle-bound orexin-B: a neuropeptide involved in the sleep/awake cycle and feeding regulation.The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding.The hypocretins: setting the arousal threshold.Functions of the orexinergic/hypocretinergic system.Modeling of the OX1R-orexin-A complex suggests two alternative binding modes.Crucial role of the orexin-B C-terminus in the induction of OX1 receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis.Hypocretin/Orexin neuropeptides: participation in the control of sleep-wakefulness cycle and energy homeostasis.Truncated Orexin Peptides: Structure-Activity Relationship StudiesHypocretins and the neurobiology of sleep-wake mechanisms.Challenges in the development of therapeutics for narcolepsy.Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.The NMR-derived conformation of orexin-A: an orphan G-protein coupled receptor agonist involved in appetite regulation and sleep.CD4+ T-Cell Reactivity to Orexin/Hypocretin in Patients With Narcolepsy Type 1.The Human Orexin/Hypocretin Receptor Crystal Structures.The orexinergic system in rainbow trout Oncorhynchus mykiss and its regulation by dietary lipids.Orexin 2 receptor can bind orexin-B neuropeptide
P2860
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P2860
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@ast
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@en
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@nl
type
label
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@ast
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@en
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@nl
prefLabel
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@ast
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@en
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@nl
P2093
P2860
P1433
P1476
Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B
@en
P2093
P2860
P356
10.1046/J.1432-1327.1999.00911.X
P407
P577
1999-12-01T00:00:00Z