Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.

Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.

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http://www.wikidata.org/entity/Q41807597
Unmet needs of patients with narcolepsy: perspectives on emerging treatment optionsUsing the fragment molecular orbital method to investigate agonist-orexin-2 receptor interactionsHistory of narcolepsy at Stanford University.Beyond Membrane Protein Structure: Drug Discovery, Dynamics and Difficulties.A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding DomainModeling of the OX1R-orexin-A complex suggests two alternative binding modes.GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.Crucial role of the orexin-B C-terminus in the induction of OX1 receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis.Orexin/hypocretin based pharmacotherapies for the treatment of addiction: DORA or SORA?Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models.Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case.What can we learn from molecular dynamics simulations for GPCR drug design?GPCR Homology Model Generation for Lead Optimization.
P2860

Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.

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http://www.wikidata.org/entity/Q41807597
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
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name
Toward an understanding of ago ...... and site-directed mutagenesis.
@en
type
label
Toward an understanding of ago ...... and site-directed mutagenesis.
@en
prefLabel
Toward an understanding of ago ...... and site-directed mutagenesis.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Toward an understanding of ago ...... and site-directed mutagenesis.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932