The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins
about
Werner SyndromeThe spectrum of WRN mutations in Werner syndrome patientsContribution of domain structure to the RNA 3' end processing and degradation functions of the nuclear exosome subunit Rrp6p.The RecQ DNA helicases in DNA repairHuman RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptideAnalysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein AModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesManipulating mitotic recombination in the zebrafish embryo through RecQ helicasesDomain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ familyTelomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicaseThe C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stabilityStructural and functional characterizations reveal the importance of a zinc binding domain in Bloom's syndrome helicaseThe Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNATopography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domainHigh-resolution structure of the E.coli RecQ helicase catalytic coreCrystal structure of the HRDC domain of human Werner syndrome protein, WRNStructure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQStructure and function of the regulatory HRDC domain from human Bloom syndrome proteinThe PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding proteinRecQ helicases: caretakers of the genomeMobility in the structure of E.coli recQ helicase upon substrate binding as seen from molecular dynamics simulations.Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changesMechanisms by which Bloom protein can disrupt recombination intermediates of Okazaki fragment maturation.The RAGNYA fold: a novel fold with multiple topological variants found in functionally diverse nucleic acid, nucleotide and peptide-binding proteinsThe full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.The HRDC domain of BLM is required for the dissolution of double Holliday junctionsIdentification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivityProkaryotic and eukaryotic DNA helicases. Essential molecular motor proteins for cellular machinery.Characterization of biochemical properties of Bacillus subtilis RecQ helicaseSgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiaeSit down, relax and unwind: structural insights into RecQ helicase mechanisms.RecQ helicases: suppressors of tumorigenesis and premature aging.The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling.Structure and function of RecQ DNA helicases.Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.Human RecQ helicases in DNA repair, recombination, and replication.Intrinsic ssDNA annealing activity in the C-terminal region of WRN.Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stabilityGenomic and Metagenomic Analysis of Diversity-Generating Retroelements Associated with Treponema denticola.
P2860
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P2860
The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The three-dimensional structur ...... er and Bloom syndrome proteins
@ast
The three-dimensional structur ...... er and Bloom syndrome proteins
@en
The three-dimensional structur ...... er and Bloom syndrome proteins
@nl
type
label
The three-dimensional structur ...... er and Bloom syndrome proteins
@ast
The three-dimensional structur ...... er and Bloom syndrome proteins
@en
The three-dimensional structur ...... er and Bloom syndrome proteins
@nl
prefLabel
The three-dimensional structur ...... er and Bloom syndrome proteins
@ast
The three-dimensional structur ...... er and Bloom syndrome proteins
@en
The three-dimensional structur ...... er and Bloom syndrome proteins
@nl
P2093
P50
P3181
P1433
P1476
The three-dimensional structur ...... er and Bloom syndrome proteins
@en
P2093
P304
P3181
P356
10.1016/S0969-2126(00)88346-X
P577
1999-12-01T00:00:00Z