Structure of the heterodimeric complex between CAD domains of CAD and ICAD
about
The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequenceIdentification of ICAD-derived peptides capable of inhibiting caspase-activated DNaseSolution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic networkAberrant caspase-activated DNase (CAD) transcripts in human hepatoma cellsA multi-factor model for caspase degradome predictionSolution structure of a ubiquitin-like domain from tubulin-binding cofactor B.Targeting the OB-Folds of Replication Protein A with Small MoleculesMomordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways.Crystallization and preliminary X-ray crystallographic studies of the CIDE-domain complex between Drep2 and Drep3 from Drosophila melanogaster.The protein structures that shape caspase activity, specificity, activation and inhibition.Systematic identification of phosphorylation-mediated protein interaction switches.Crystallization and preliminary X-ray crystallographic studies of the CIDE-N domain of CIDE-3.Stable overexpression of DNA fragmentation factor in T-47D cells: sensitization of breast cancer cells to apoptosis in response to acetazolamide and sulfabenzamide.Sensitization of breast cancer cells to doxorubicin via stable cell line generation and overexpression of DFF40.Structural insight into CIDE domains: the Janus face of CIDEs.Identification of functionally relevant histidine residues in the apoptotic nuclease CAD.Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD.The effect of ICAD-S on the formation and intracellular distribution of a nucleolytically active caspase-activated DNase.Oligomerization state of the DNA fragmentation factor in normal and apoptotic cells.Inhibitor of caspase-activated DNase expression enhances caspase-activated DNase expression and inhibits oxidative stress-induced chromosome breaks at the mixed lineage leukaemia gene in nasopharyngeal carcinoma cells.Purification, crystallization and preliminary X-ray crystallographic studies of Drep2 CIDE domain.Co-translational folding of caspase-activated DNase with Hsp70, Hsp40, and inhibitor of caspase-activated DNase.Molecular recognition in dimerization between PB1 domains.General interaction mode of CIDE:CIDE complex revealed by a mutation study of the Drep2 CIDE domain.Interaction mode of CIDE family proteins in fly: DREP1 and DREP3 acidic surfaces interact with DREP2 and DREP4 basic surfaces.CIDE domains form functionally important higher-order assemblies for DNA fragmentation.Sequence elements in both subunits of the DNA fragmentation factor are essential for its nuclear transport.siRNA-mediated knock-down of DFF45 amplifies doxorubicin therapeutic effects in breast cancer cells.A putative role of Drep1 in apoptotic DNA fragmentation system in fly is mediated by direct interaction with Drep2 and Drep4.
P2860
Q24292005-4F47D246-7F7C-40C8-9C43-1CDFB9D56E7FQ24338846-B3D0E08D-5B01-4B05-B30D-6BB7041CEFADQ24629962-3FFC6C87-F0D2-4AAD-A6AC-DE9B120DFE98Q24630357-F278D253-E1B4-4CF5-AA3B-27860F46D8B9Q24656941-111F2B36-981C-468D-A0FB-0B74FD120034Q30951290-E135FA98-DAA6-4FDB-AD0D-2BDC3F8F1900Q33206776-7BE3EEC0-6DCA-4205-A71B-462218E270EFQ33781249-D28F5194-B2CC-4A2B-9636-46CEFE2DFF24Q34034102-FB524EBE-FE0C-4B2C-93D2-425E480AE9CBQ34823830-9D80CA20-4BBD-4CAE-BA31-0EC5418E97A8Q35902423-0B9C95B5-0616-47E5-BF9C-28E76386398AQ36323918-4352EC4E-473F-4936-BD3C-40D4F98FD2B8Q37281246-22A8B5A9-11AF-4AE2-8425-35B8197ACC89Q37554712-5DBFE300-BF70-4F37-BDE6-14E43555B980Q37562199-E28EF9D4-0949-4C04-805F-39AB61A0959CQ38285525-B3632079-F363-45B1-A7AF-905916EFE7E9Q39230298-6B1B2926-E149-46FD-BEDF-6CEB7B177B36Q39535749-69A4A29A-6C9B-4FC7-8327-4A8019D33067Q39681907-543DBFE2-77C2-401D-8A91-60668E8A743EQ40365629-24E6AFA6-94BB-4BF8-BF66-C600B3161C8DQ41175425-8F3C47DB-7AF4-47CC-82DE-FCB0D627015FQ41995689-0BD2C62B-73E8-42F0-8E58-527AF2AF6162Q43810195-26DE0FA3-8BB4-4BA1-B517-5EB92F2566CCQ44550518-8A0D1D05-5CE5-4D1D-8CA3-ABCC91E0AA81Q47072205-11BDC5BA-3DB4-4867-A762-85C082771F85Q47156521-D18F6AAB-F59A-4AB2-8B6D-4EB963479425Q49556652-C2C01C91-DCDE-4EFF-A02D-FD9E04CB6B73Q50336589-EF5E0937-B00B-4772-9A54-98788869A583Q51770322-7470B2C7-ACF4-4D57-82C6-68DAAFE6A764Q52751354-C087CFEF-221E-4D3A-A083-A1879E4E35DF
P2860
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
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2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@ast
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@en
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@nl
type
label
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@ast
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@en
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@nl
prefLabel
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@ast
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@en
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@nl
P2093
P356
P1476
Structure of the heterodimeric complex between CAD domains of CAD and ICAD
@en
P2093
P304
P356
10.1038/77957
P407
P577
2000-08-01T00:00:00Z