Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core
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Perampanel inhibition of AMPA receptor currents in cultured hippocampal neuronsAllosteric control of an ionotropic glutamate receptor with an optical switch.Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptorsTargeting AMPA receptor gating processes with allosteric modulators and mutationsSubunit modification and association in VR1 ion channels.Structure, Dynamics, and Allosteric Potential of Ionotropic Glutamate Receptor N-Terminal DomainsFunctional insights from glutamate receptor ion channel structuresEmerging models of glutamate receptor ion channel structure and functionSize matters in activation/inhibition of ligand-gated ion channelsAMPA receptors as a molecular target in epilepsy therapyHeterologous Expression and Functional Analysis of Rice GLUTAMATE RECEPTOR-LIKE Family Indicates its Role in Glutamate Triggered Calcium Flux in Rice Roots.Computational study of synthetic agonist ligands of ionotropic glutamate receptorsGluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonistsTuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changesMechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding coreCrystal structure of a histidine kinase sensor domain with similarity to periplasmic binding proteinsConformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structuresPartial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acidIonotropic glutamate-like receptor 2 binds D-serine and glycineTARP auxiliary subunits switch AMPA receptor antagonists into partial agonistsMolecular Basis of Kainate Receptor Modulation by SodiumMolecular mechanism of ligand recognition by NR3 subtype glutamate receptors6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) Forms an Irreversible Bond To the Active Site of the GluR2 AMPA Receptor †Structure of the S1S2 glutamate binding domain of GLuR3Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4Correlating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists †Mechanisms of Antagonism of the GluR2 AMPA Receptor: Structure and Dynamics of the Complex of Two Willardiine Antagonists with the Glutamate Binding DomainFull Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-DideoxyneodysiherbaineStability of ligand-binding domain dimer assembly controls kainate receptor desensitizationStructure-based design of a periplasmic binding protein antagonist that prevents domain closureCrystal structure and association behaviour of the GluR2 amino-terminal domainProbing the Allosteric Modulator Binding Site of GluR2 with Thiazide DerivativesStructure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunitX-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptorEnhanced Efficacy without Further Cleft Closure: Reevaluating Twist as a Source of Agonist Efficacy in AMPA ReceptorsMolecular Mechanism of Flop Selectivity and Subsite Recognition for an AMPA Receptor Allosteric Modulator: Structures of GluA2 and GluA3 in Complexes with PEPABinding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonistsCrystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal DomainsCrystal structure of the glutamate receptor GluA1 N-terminal domainDynamics and allosteric potential of the AMPA receptor N-terminal domain
P2860
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P2860
Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Mechanisms for activation and ...... the GluR2 ligand binding core
@ast
Mechanisms for activation and ...... the GluR2 ligand binding core
@en
Mechanisms for activation and ...... the GluR2 ligand binding core
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type
label
Mechanisms for activation and ...... the GluR2 ligand binding core
@ast
Mechanisms for activation and ...... the GluR2 ligand binding core
@en
Mechanisms for activation and ...... the GluR2 ligand binding core
@nl
prefLabel
Mechanisms for activation and ...... the GluR2 ligand binding core
@ast
Mechanisms for activation and ...... the GluR2 ligand binding core
@en
Mechanisms for activation and ...... the GluR2 ligand binding core
@nl
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Mechanisms for activation and ...... the GluR2 ligand binding core
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P2093
P304
P3181
P356
10.1016/S0896-6273(00)00094-5
P407
P577
2000-10-01T00:00:00Z