Folate-binding triggers the activation of folylpolyglutamate synthetase
about
Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folatesThree-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substateStructure of an Amide Bond Forming F420:γγ-glutamyl Ligase from Archaeoglobus Fulgidus - A Member of a New Family of Non-ribosomal Peptide SynthasesStructures ofMycobacterium tuberculosisfolylpolyglutamate synthase complexed with ADP and AMPPCPFlexOracle: predicting flexible hinges by identification of stable domains.Phase I study of pemetrexed and pegylated liposomal doxorubicin in patients with refractory breast, ovarian, primary peritoneal, or fallopian tube cancer.Concentration-dependent processivity of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetase.Streptococcus pneumoniae folate biosynthesis responds to environmental CO2 levelsBinding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemiaThe folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery.Synthesis of (6R)- and (6S)-5,10-dideazatetrahydrofolate oligo-gamma-glutamates: kinetics of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetasePurification, crystallization and preliminary X-ray analysis of Mycobacterium tuberculosisfolylpolyglutamate synthase (MtbFPGS).Cytoplasmic steps of peptidoglycan biosynthesis.Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments.Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery.Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance.Escherichia coli FolC structure reveals an unexpected dihydrofolate binding site providing an attractive target for anti-microbial therapy.
P2860
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P2860
Folate-binding triggers the activation of folylpolyglutamate synthetase
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Folate-binding triggers the activation of folylpolyglutamate synthetase
@ast
Folate-binding triggers the activation of folylpolyglutamate synthetase
@en
Folate-binding triggers the activation of folylpolyglutamate synthetase
@nl
type
label
Folate-binding triggers the activation of folylpolyglutamate synthetase
@ast
Folate-binding triggers the activation of folylpolyglutamate synthetase
@en
Folate-binding triggers the activation of folylpolyglutamate synthetase
@nl
prefLabel
Folate-binding triggers the activation of folylpolyglutamate synthetase
@ast
Folate-binding triggers the activation of folylpolyglutamate synthetase
@en
Folate-binding triggers the activation of folylpolyglutamate synthetase
@nl
P2093
P356
P1476
Folate-binding triggers the activation of folylpolyglutamate synthetase
@en
P2093
P304
P356
10.1006/JMBI.2001.4815
P407
P577
2001-07-01T00:00:00Z