Structures ofMycobacterium tuberculosisfolylpolyglutamate synthase complexed with ADP and AMPPCP
about
Reversible Post-Translational Carboxylation Modulates the Enzymatic Activity of N -Acetyl- l -ornithine TranscarbamylaseMycobacterium tuberculosis folate metabolism and the mechanistic basis for para-aminosalicylic acid susceptibility and resistancepara-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosisBinding pocket alterations in dihydrofolate synthase confer resistance to para-aminosalicylic acid in clinical isolates of Mycobacterium tuberculosis.Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery.Recognizing drug targets using evolutionary information: implications for repurposing FDA-approved drugs against Mycobacterium tuberculosis H37Rv.Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition.CO₂directly modulates connexin 26 by formation of carbamate bridges between subunits.Antifragility and Tinkering in Biology (and in Business) Flexibility Provides an Efficient Epigenetic Way to Manage Risk.
P2860
Q27663977-4801914A-B78D-4320-BCDF-E19D4A180A0CQ28082718-1D6FAB9B-0835-4F4D-AF26-D6D74398B201Q34351796-9EFD3026-2E3D-4C75-9CE3-D493B0EF685EQ37643668-4FFDC980-DB65-470D-AB46-39ADCB9EE00CQ38792855-AB9E5239-91C1-4413-8412-D59CA9180CDCQ40475389-3984024A-8B85-4201-A2C4-5F2FACB5BE1EQ40793245-F9E3A06B-B8BC-49ED-B784-2823094842ACQ41892709-67B74546-F284-4186-B3B5-34A8DF956CC8Q41962414-6364EE16-3D11-4572-8D1F-3851AF8F6753
P2860
Structures ofMycobacterium tuberculosisfolylpolyglutamate synthase complexed with ADP and AMPPCP
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@ast
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@en
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@nl
type
label
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@ast
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@en
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@nl
prefLabel
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@ast
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@en
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@nl
P2093
P2860
P1476
Structures ofMycobacterium tub ...... complexed with ADP and AMPPCP
@en
P2093
Clyde A Smith
Paul G Young
Peter Metcalf
P2860
P304
P356
10.1107/S0907444908012262
P577
2008-07-01T00:00:00Z