Domain alternation switches B(12)-dependent methionine synthase to the activation conformation
about
Natural history of S-adenosylmethionine-binding proteinsStructures of the N-terminal modules imply large domain motions during catalysis by methionine synthaseCrystal structure and solution characterization of the activation domain of human methionine synthaseA disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactorStructural Characterization of a 140° Domain Movement in the Two-Step Reaction Catalyzed by 4-Chlorobenzoate:CoA Ligase † ‡The 1.6 Å Crystal Structure of Mycobacterium smegmatis MshC: The Penultimate Enzyme in the Mycothiol Biosynthetic Pathway †Insights into the reactivation of cobalamin-dependent methionine synthaseVisualizing molecular juggling within a B12-dependent methyltransferase complexStructure of the cobalamin-binding protein of a putativeO-demethylase fromDesulfitobacterium hafnienseDCB-2Catalysis of methyl group transfers involving tetrahydrofolate and B(12)Ethanol lowers glutathione in rat liver and brain and inhibits methionine synthase in a cobalamin-dependent mannerInsight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex.Comparative proteome analysis of embryo and endosperm reveals central differential expression proteins involved in wheat seed germinationAge-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autismMacromolecular juggling by ubiquitylation enzymes.Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediateSpectroscopic study of the cobalamin-dependent methionine synthase in the activation conformation: effects of the Y1139 residue and S-adenosylmethionine on the B12 cofactor.Probing the role of the histidine 759 ligand in cobalamin-dependent methionine synthase.Cobalamin- and corrinoid-dependent enzymesFactors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthaseComputational discovery of specificity-conferring sites in non-ribosomal peptide synthetases.A method for prediction of the locations of linker regions within large multifunctional proteins, and application to a type I polyketide synthase.Mechanism of MenE inhibition by acyl-adenylate analogues and discovery of novel antibacterial agentsAlternatively Spliced Methionine Synthase in SH-SY5Y Neuroblastoma Cells: Cobalamin and GSH Dependence and Inhibitory Effects of Neurotoxic Metals and Thimerosal.Ligand trans influence governs conformation in cobalamin-dependent methionine synthaseCobalamin-dependent and cobamide-dependent methyltransferasesBiography of Martha L. LudwigA love affair with vitamins.Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase.Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain.Mechanism of 4-chlorobenzoate:coenzyme a ligase catalysis.Spectroscopic and computational characterization of the base-off forms of cob(II)alamin.Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase-methionine synthase reductase complex.Cysteine and methionine catabolism
P2860
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P2860
Domain alternation switches B(12)-dependent methionine synthase to the activation conformation
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Domain alternation switches B( ...... to the activation conformation
@ast
Domain alternation switches B( ...... to the activation conformation
@en
Domain alternation switches B( ...... to the activation conformation
@nl
type
label
Domain alternation switches B( ...... to the activation conformation
@ast
Domain alternation switches B( ...... to the activation conformation
@en
Domain alternation switches B( ...... to the activation conformation
@nl
prefLabel
Domain alternation switches B( ...... to the activation conformation
@ast
Domain alternation switches B( ...... to the activation conformation
@en
Domain alternation switches B( ...... to the activation conformation
@nl
P2093
P356
P1476
Domain alternation switches B( ...... to the activation conformation
@en
P2093
Brett W Lennon
Donald P Huddler
Katherine A Pattridge
Martha L Ludwig
Rowena G Matthews
Vahe Bandarian
P356
10.1038/NSB738
P577
2002-01-01T00:00:00Z