Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediate
about
The 2.1 Å crystal structure of an acyl-CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl-binding pocket for small branched acyl substratesSelective inhibition of Biotin Protein Ligase from Staphylococcus aureusSynthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosisGeneral platform for systematic quantitative evaluation of small-molecule permeability in bacteria.Improved Synthesis of Biotinol-5'-AMP: Implications for Antibacterial Discovery.Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosaStable analogues of OSB-AMP: potent inhibitors of MenE, the o-succinylbenzoate-CoA synthetase from bacterial menaquinone biosynthesisMechanism of MenE inhibition by acyl-adenylate analogues and discovery of novel antibacterial agentsAdenylating enzymes in Mycobacterium tuberculosis as drug targets.Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase.Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase.Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes.Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase.Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes.Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode.Stereoselective Synthesis, Docking, and Biological Evaluation of Difluoroindanediol-Based MenE Inhibitors as Antibiotics.
P2860
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P2860
Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediate
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@ast
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@en
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@nl
type
label
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@ast
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@en
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@nl
prefLabel
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@ast
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@en
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@nl
P2093
P2860
P356
P1433
P1476
Bacillus anthracis o-succinylb ...... king its reaction intermediate
@en
P2093
Andrew D Mesecar
Dae-Hwan Suk
P2860
P304
12434-12447
P356
10.1021/BI801311D
P407
P50
P577
2008-11-01T00:00:00Z