Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin
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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoformsCharacterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreasFrom genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathwaysMutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degenerationAnalysis of Escherichia coli nicotinate mononucleotide adenylyltransferase mutants in vivo and in vitro.Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesisBifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD MetabolismStructure of nicotinic acid mononucleotide adenylyltransferase fromBacillus anthracisNicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensisStructure and Mechanism of a Eukaryotic FMN AdenylyltransferaseTargeting NAD Biosynthesis in Bacterial Pathogens: Structure-Based Development of Inhibitors of Nicotinate Mononucleotide Adenylyltransferase NadDComplexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and ImprovementMutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophyExome sequencing identifies NMNAT1 mutations as a cause of Leber congenital amaurosisNicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvageMolecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.Comparative genomics of NAD biosynthesis in cyanobacteria.Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotideCharacterization of Leber Congenital Amaurosis-associated NMNAT1 MutantsNicotinamide mononucleotide adenylyltransferase displays alternate binding modes for nicotinamide nucleotidesHidden Genetic Variation in LCA9-Associated Congenital Blindness Explained by 5'UTR Mutations and Copy-Number Variations of NMNAT1.Diversification of NAD biological role: the importance of location.Identification of the nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi.Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship.NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAADStructural insights into Plasmodium falciparum nicotinamide mononucleotide adenylyltransferase: oligomeric assemblyA close look at NAD biosynthesisCorrigendum to: Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN (FEBS 25964)
P2860
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P2860
Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@ast
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@en
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@nl
type
label
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@ast
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@en
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@nl
prefLabel
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@ast
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@en
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@nl
P2093
P2860
P356
P1476
Structure of human nicotinamid ...... the oncolytic agent tiazofurin
@en
P2093
Andrei L Osterman
Derk D Binns
Hong Zhang
Oleg Kurnasov
Tianjun Zhou
Victor E Marquez
P2860
P304
P356
10.1074/JBC.M111469200
P407
P577
2002-04-12T00:00:00Z