Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor - Wikidata - awgldk - TriplyDB

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

http://www.wikidata.org/entity/Q27639868

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The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1 Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Structure and mechanism of non-histone protein acetyltransferase enzymes Protein lysine acetylation by p300/CBP Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.Mechanistic and Structural Analysis of Human Spermidine/Spermine N 1 -Acetyltransferase † , ‡Crystal structure of RimI fromSalmonella typhimurium LT2, the GNAT responsible for Nα-acetylation of ribosomal protein S18 Structure of the complex of Neisseria gonorrhoeae N-acetyl-l-glutamate synthase with a bound bisubstrate analog Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy A random sequential mechanism of aminoglycoside acetylation by Mycobacterium tuberculosis Eis protein Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor Writers and readers of histone acetylation: structure, mechanism, and inhibition Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.Small molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates.Processing mechanism and substrate selectivity of the core NuA4 histone acetyltransferase complex.Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise.Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors.PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1.Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design.Structural basis for acyl-group discrimination by human Gcn5L2 Chemical probes for histone-modifying enzymes Histone acetyltransferase inhibitors and preclinical studies.Regulation of a Protein Acetyltransferase in Myxococcus xanthus by the Coenzyme NADP.Chemical Biology for Investigating Epigenetic Functions of Lysine Acetyltransferases (KATs).Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF.p300/CBP-associated factor drives DEK into interchromatin granule clusters.Structural Basis of Eco1-Mediated Cohesin Acetylation.Characterization, localization, essentiality, and high-resolution crystal structure of glucosamine 6-phosphate N-acetyltransferase from Trypanosoma brucei.Probing the reaction coordinate of the p300/CBP histone acetyltransferase with bisubstrate analogs.Involvement of Hat1p (Kat1p) catalytic activity and subcellular localization in telomeric silencing.Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.Structural and functional features of lysine acetylation of plant and animal tubulins.KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors.

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P2860

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

http://www.wikidata.org/entity/Q27639868

description

2002 nî lūn-bûn

@nan

2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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name

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

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type

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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

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prefLabel

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

@ast

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

@en

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

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P2093

Arienne N Poux

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Cheol M Kim

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Marek Cebrat

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Philip A Cole

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P2860

Acetylation of histones and transcription-related factors

Mechanism-based inhibition of the melatonin rhythm enzyme: pharmacologic exploitation of active site functional plasticity

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A

Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases

X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition

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14065-70

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scholarly article

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10.1073/PNAS.222373899

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22

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99

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Ronen Marmorstein

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2002-10-29T00:00:00Z

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11071598

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12391296

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137837

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