Mechanism-based inhibition of the melatonin rhythm enzyme: pharmacologic exploitation of active site functional plasticity
about
cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activationDe novo discovery of serotonin N-acetyltransferase inhibitorsProtein lysine acetylation by p300/CBPInvestigation of the roles of catalytic residues in serotonin N-acetyltransferaseStructure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitorStructural and biochemical characterization of a trapped coenzyme A adduct ofCaenorhabditis elegansglucosamine-6-phosphateN-acetyltransferase 1Substrate specificity and inhibition studies of human serotonin N-acetyltransferaseNew substrate analogues of human serotonin N-acetyltransferase produce in situ specific and potent inhibitorsReversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMPin-silico study of arylalkylamine-nacetyltransferase enzyme to regulate circadian rhythmicityEnzymatic and cellular study of a serotonin N-acetyltransferase phosphopantetheine-based prodrugMultisubstrate adduct inhibitors: drug design and biological tools.The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an active site base important for acetyl transfer.Ghrelin O-acyltransferase (GOAT) and energy metabolism.Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli.Design, synthesis and in vitro evaluation of novel benzo[b]thiophene derivatives as serotonin N-acetyltransferase (AANAT) inhibitors.
P2860
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P2860
Mechanism-based inhibition of the melatonin rhythm enzyme: pharmacologic exploitation of active site functional plasticity
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mechanism-based inhibition of ...... ive site functional plasticity
@ast
Mechanism-based inhibition of ...... ive site functional plasticity
@en
Mechanism-based inhibition of ...... ive site functional plasticity
@nl
type
label
Mechanism-based inhibition of ...... ive site functional plasticity
@ast
Mechanism-based inhibition of ...... ive site functional plasticity
@en
Mechanism-based inhibition of ...... ive site functional plasticity
@nl
prefLabel
Mechanism-based inhibition of ...... ive site functional plasticity
@ast
Mechanism-based inhibition of ...... ive site functional plasticity
@en
Mechanism-based inhibition of ...... ive site functional plasticity
@nl
P2093
P2860
P356
P1476
Mechanism-based inhibition of ...... ive site functional plasticity
@en
P2093
E M Khalil
J De Angelis
P2860
P304
12418-12423
P356
10.1073/PNAS.96.22.12418
P407
P50
P577
1999-10-01T00:00:00Z