Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase
about
Crystal structures of Geobacillus stearothermophilus alpha-glucuronidase complexed with its substrate and products: mechanistic implicationsCrystal structure of α-amylase from Oryza sativa: molecular insights into enzyme activity and thermostabilitySubsite mapping of human salivary alpha-amylase and the mutant Y151MMolecular dynamics of mesophilic-like mutants of a cold-adapted enzyme: insights into distal effects induced by the mutationsRole of active-site residues of dispersin B, a biofilm-releasing beta-hexosaminidase from a periodontal pathogen, in substrate hydrolysis.Using Carbohydrate Interaction Assays to Reveal Novel Binding Sites in Carbohydrate Active Enzymes.Probing the role of aromatic residues at the secondary saccharide-binding sites of human salivary alpha-amylase in substrate hydrolysis and bacterial bindingOccurrence and functional significance of secondary carbohydrate binding sites in glycoside hydrolases.α-Amylase: an enzyme specificity found in various families of glycoside hydrolases.Functional roles of H98 and W99 and β2α2 loop dynamics in the α-l-arabinofuranosidase from Thermobacillus xylanilyticus.Oligosaccharide binding to barley alpha-amylase 1.Putative implication of alpha-amylase loop 7 in the mechanism of substrate binding and reaction products release.Human salivary alpha-amylase Trp58 situated at subsite -2 is critical for enzyme activity.Oleanolic acid and ursolic acid as potential inhibitors of human salivary α-amylase: insights from in vitro assays and in silico simulations.Structure of human salivary alpha-amylase crystallized in a C-centered monoclinic space groupEnhancement of the alcoholytic activity of alpha-amylase AmyA from Thermotoga maritima MSB8 (DSM 3109) by site-directed mutagenesis.Molecular cloning of soluble trehalase from Chironomus riparius larvae, its heterologous expression in Escherichia coli and bioinformatic analysis.Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple substrate recognition mechanism.Construction of chimeric glucansucrases for analyzing substrate-binding regions that affect the structure of glucan products.Secondary substrate binding strongly affects activity and binding affinity of Bacillus subtilis and Aspergillus niger GH11 xylanases.Pouteria ramiflora extract inhibits salivary amylolytic activity and decreases glycemic level in mice.Functional annotation of the mesophilic-like character of mutants in a cold-adapted enzyme by self-organising map analysis of their molecular dynamics.Characterization of BGTG-1, a tergal gland-secreted alpha-amylase, from the German cockroach, Blattella germanica (L.).Acute metabolic actions of the major polyphenols in chamomile: an in vitro mechanistic study on their potential to attenuate postprandial hyperglycaemia.Putative salivary protein biomarkers for the diagnosis of oral lichen planus: a case-control study.Modeling and biochemical analysis of the activity of antibiofilm agent Dispersin B
P2860
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P2860
Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Probing the role of a mobile l ...... vity of human salivary amylase
@ast
Probing the role of a mobile l ...... vity of human salivary amylase
@en
Probing the role of a mobile l ...... vity of human salivary amylase
@nl
type
label
Probing the role of a mobile l ...... vity of human salivary amylase
@ast
Probing the role of a mobile l ...... vity of human salivary amylase
@en
Probing the role of a mobile l ...... vity of human salivary amylase
@nl
prefLabel
Probing the role of a mobile l ...... vity of human salivary amylase
@ast
Probing the role of a mobile l ...... vity of human salivary amylase
@en
Probing the role of a mobile l ...... vity of human salivary amylase
@nl
P2093
P3181
P1476
Probing the role of a mobile l ...... vity of human salivary amylase
@en
P2093
Chandran Ragunath
Narayanan Ramasubbu
Prasunkumar J Mishra
P304
P3181
P356
10.1016/S0022-2836(02)01326-8
P407
P577
2003-01-31T00:00:00Z