Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
about
Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigenCrystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptorThe Crystal Structure of C2a, the Catalytic Fragment of Classical Pathway C3 and C5 Convertase of Human ComplementStructure of Collagen Receptor Integrin 1I Domain Carrying the Activating Mutation E317AStable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug DesignStructure ofStreptococcus agalactiaetip pilin GBS104: a model for GBS pili assembly and host interactionsBiology and structure of leukocyte β 2 integrins and their role in inflammationExtracellular protein disulfide isomerase regulates ligand-binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammationCombinatorial libraries against libraries for selecting neoepitope activation-specific antibodies.Anthrax toxin receptor 1/tumor endothelial marker 8: mutation of conserved inserted domain residues overrides cytosolic control of protective antigen bindingDirected evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.The simulation of stress fibre and focal adhesion development in cells on patterned substrates.Simulation of the cytoskeletal response of cells on grooved or patterned substrates.The αE(CD103)β7 integrin interacts with oral and skin keratinocytes in an E-cadherin-independent manner*.Dual function for a unique site within the beta2I domain of integrin alphaMbeta2.Novel activating and inactivating mutations in the integrin beta1 subunit A domain.Identification of novel agonists of the integrin CD11b/CD18.Rationally designed integrin beta3 mutants stabilized in the high affinity conformation.The hydrophobic contacts between the center of the βI domain and the α1/α7 helices are crucial for the low-affinity state of integrin α4 β7.Integrin genes and susceptibility to human melanoma.
P2860
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P2860
Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
description
2003 nî lūn-bûn
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2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
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name
Engineered allosteric mutants ...... uctural and functional studies
@ast
Engineered allosteric mutants ...... uctural and functional studies
@en
Engineered allosteric mutants ...... uctural and functional studies
@nl
type
label
Engineered allosteric mutants ...... uctural and functional studies
@ast
Engineered allosteric mutants ...... uctural and functional studies
@en
Engineered allosteric mutants ...... uctural and functional studies
@nl
prefLabel
Engineered allosteric mutants ...... uctural and functional studies
@ast
Engineered allosteric mutants ...... uctural and functional studies
@en
Engineered allosteric mutants ...... uctural and functional studies
@nl
P2860
P3181
P356
P1433
P1476
Engineered allosteric mutants ...... uctural and functional studies
@en
P2093
Clare J McCleverty
Robert C Liddington
P2860
P3181
P356
10.1042/BJ20021273
P407
P577
2003-05-15T00:00:00Z