Binding of Uridine 5‘-Diphosphate in the “Basic Patch” of the Zinc Deacetylase LpxC and Implications for Substrate Binding † , ‡

Binding of Uridine 5‘-Diphosphate in the “Basic Patch” of the Zinc Deacetylase LpxC and Implications for Substrate Binding † , ‡

Item
http://www.wikidata.org/entity/Q27640825
Q27643348
sameAs
Lipid A modification systems in gram-negative bacteriaStructure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand bindingCrystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitorSpecies-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic DesignStructure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090,Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffoldStructure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton TransferTranslating slow-binding inhibition kinetics into cellular and in vivo effectsCrystal structure of A. aeolicus LpxC with bound product suggests alternate deacetylation mechanism.Activation of Escherichia coli UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase by Fe2+ yields a more efficient enzyme with altered ligand affinity.Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC.Design, Modeling and Synthesis of 1,2,3-Triazole-Linked Nucleoside-Amino Acid Conjugates as Potential Antibacterial Agents.
P2860

Binding of Uridine 5‘-Diphosphate in the “Basic Patch” of the Zinc Deacetylase LpxC and Implications for Substrate Binding † , ‡

Item
http://www.wikidata.org/entity/Q27640825
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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type
label
Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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Binding of uridine 5'-diphosph ...... ications for substrate binding
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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P2093
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Binding of Uridine 5‘-Diphosph ...... ns for Substrate Binding † , ‡
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932