Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar

Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar

Item
http://www.wikidata.org/entity/Q27640877
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligandsDesign novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approachA compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative abilityVirtual Screening as a Technique for PPAR Modulator Discovery.Targeting Peroxisome Proliferator-Activated Receptors Using Thiazolidinediones: Strategy for Design of Novel Antidiabetic DrugsRat Urinary Bladder Carcinogenesis by Dual-Acting PPARalpha + gamma AgonistsActivation of PPARδ: from computer modelling to biological effects.Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics.Synthesis and anti-diabetic activity of (RS)-2-ethoxy-3-{4-[2-(4-trifluoro-methanesulfonyloxy-phenyl)-ethoxy]-phenyl}-propionic acid.Molecular modelling study of the PPARγ receptor in relation to the mode of action/adverse outcome pathway framework for liver steatosis.Dandamycin and chandrananimycin E, benzoxazines from Streptomyces griseus.Synthesis and evaluation of (S)-2-ethoxy-3-phenylpropanoic acid derivatives as insulin-sensitizing agents.Generalized cellular hypertrophy is induced by a dual-acting PPAR agonist in rat urinary bladder urothelium in vivo.Hypolipidaemic mechanisms of action of CM108 (a flavone derivative) in hyperlipidaemic rats.Biomarkers for early effects of carcinogenic dual-acting PPAR agonists in rat urinary bladder urothelium in vivo.Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes.SAR and Computer-Aided Drug Design Approaches in the Discovery of Peroxisome Proliferator-Activated ReceptorγActivators: A Perspective
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Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar

Item
http://www.wikidata.org/entity/Q27640877
description
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article scientifique (publié 2003/04/10)
@fr
articolo scientifico (pubblicato il 2003/04/10)
@it
artigo científico (publicado na 2003/04/10)
@pt
artículu científicu espublizáu en 2003
@ast
im April 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 10 April 2003)
@en
vedecký článok (publikovaný 2003/04/10)
@sk
vetenskaplig artikel (publicerad på 2003/04/10)
@sv
name
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@ast
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@en
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@nl
type
label
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@ast
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@en
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@nl
prefLabel
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@ast
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@en
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Synthesis and biological and s ...... pha/gamma agonist ragaglitazar
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698