Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B

Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B

Item
http://www.wikidata.org/entity/Q27641255
Protein pockets: inventory, shape, and comparisonInhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages.Protein tyrosine phosphatase 1B inhibitors: a molecular level legitimate approach for the management of diabetes mellitus.Recent advances in protein tyrosine phosphatase 1B inhibitors.NMR-based techniques in the hit identification and optimisation processes.Adipose targets for obesity drug development.New strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB.Fragment-based drug discovery using the SHAPES method.Ligand efficiency indices for effective drug discovery.In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase.Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites.Computational revelation of binding mechanisms of inhibitors to endocellular protein tyrosine phosphatase 1B using molecular dynamics simulations.Prediction of enzyme inhibition and mode of inhibitory action based on calculation of distances between hydrogen bond donor/acceptor groups of the molecule and docking analysis: An application on the discovery of novel effective PTP1B inhibitors.
P2860

Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B

Item
http://www.wikidata.org/entity/Q27641255
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
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2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
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name
Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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type
label
Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
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P1433
P1476
Discovery and structure-activi ...... rotein tyrosine phosphatase 1B
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P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921