Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1
about
The DMAP interaction domain of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase is a substrate recognition moduleAnalysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognitionStealth proteins: in silico identification of a novel protein family rendering bacterial pathogens invisible to host immune defense.Notch receptor-ligand binding and activation: insights from molecular studiesStructure and stability of the ankyrin domain of the Drosophila Notch receptorStructural basis for autoinhibition of NotchCharacterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.Evidence for increased exposure of the Notch1 metalloprotease cleavage site upon conversion to an activated conformationQuantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch.Notch Transmembrane Domain: Secondary Structure and Topology.Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster.The molecular logic of Notch signaling--a structural and biochemical perspective.Mechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies.Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats.Human NOTCH2 Is Resistant to Ligand-independent Activation by Metalloprotease Adam17.A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module.Ectodomain shedding and intramembrane cleavage of mammalian Notch proteins is not regulated through oligomerization.The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.High-resolution crystal structure of the human Notch 1 ankyrin domain.Using UV-absorbance of intrinsic dithiothreitol (DTT) during RP-HPLC as a measure of experimental redox potential in vitro.Insights into Notch3 activation and inhibition mediated by antibodies directed against its negative regulatory region.
P2860
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P2860
Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Nuclear magnetic resonance str ...... epeat module from human Notch1
@ast
Nuclear magnetic resonance str ...... epeat module from human Notch1
@en
Nuclear magnetic resonance str ...... epeat module from human Notch1
@nl
type
label
Nuclear magnetic resonance str ...... epeat module from human Notch1
@ast
Nuclear magnetic resonance str ...... epeat module from human Notch1
@en
Nuclear magnetic resonance str ...... epeat module from human Notch1
@nl
prefLabel
Nuclear magnetic resonance str ...... epeat module from human Notch1
@ast
Nuclear magnetic resonance str ...... epeat module from human Notch1
@en
Nuclear magnetic resonance str ...... epeat module from human Notch1
@nl
P2093
P356
P1433
P1476
Nuclear magnetic resonance str ...... epeat module from human Notch1
@en
P2093
Cheryll Sanchez-Irizarry
Christopher L North
Didem Vardar
Jon C Aster
Stephen C Blacklow
P304
P356
10.1021/BI034156Y
P407
P577
2003-06-17T00:00:00Z