Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor
about
Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolaseAryl Vinyl Sulfonates and Sulfones as Active Site-Directed and Mechanism-Based Probes for Protein Tyrosine PhosphatasesUtilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase ‡Conformational Basis for Substrate Recruitment in Protein Tyrosine Phosphatase 10DInvestigation of Catalytic Loop Structure, Dynamics, and Function Relationship of Yersinia Protein Tyrosine Phosphatase by Temperature-Jump Relaxation Spectroscopy and X-ray Structural DeterminationAurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague.Derivatives of salicylic acid as inhibitors of YopH in Yersinia pestisNitropropenyl benzodioxole, an anti-infective agent with action as a protein tyrosine phosphatase inhibitorStructure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry.Activity-based probes for protein tyrosine phosphatasesA mining minima approach to exploring the docking pathways of p-nitrocatechol sulfate to YopH.Exploring Oxidovanadium(IV) Complexes as YopH Inhibitors: Mechanism of Action and Modeling Studies.Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches.Yersinia outer proteins: Yops.Aurintricarboxylic acid structure modifications lead to reduction of inhibitory properties against virulence factor YopH and higher cytotoxicityProtein tyrosine phosphatase structure-function relationships in regulation and pathogenesis.Structural insight into effector proteins of Gram-negative bacterial pathogens that modulate the phosphoproteome of their host.Design, synthesis, and evaluation of 2-(arylsulfonyl)oxiranes as cell-permeable covalent inhibitors of protein tyrosine phosphatases.The sulfogalactose moiety of sulfoglycosphingolipids serves as a mimic of tyrosine phosphate in many recognition processes. Prediction and demonstration of Src homology 2 domain/sulfogalactose binding.
P2860
Q24546215-100F5392-2F1E-4FAB-8BCF-EE36EFF6EFD0Q27650751-7F7DA0D1-ABE8-44D7-B36A-56199E9DFB2BQ27667338-0D7E0DA9-2936-4E54-8999-4A4B72CECBFDQ27675112-ECDDCD5D-2AD6-4F5D-A9B3-75CED62770B3Q27678944-9AA9ED63-4553-476E-81F4-42952D51E9C1Q31151176-D8C6CADF-CDC9-4B33-9540-1FE33657D5EBQ33609113-70D7C79D-4653-45DB-A94C-4A1D9A0CFDCCQ33815443-E3FEB266-B463-4339-91C4-4F4FA8EFB8FDQ33972838-D2894FA7-9C8C-44DC-97AB-E9B99095B4E4Q34330552-CA18ED95-13D2-4FDD-AFEA-CE2B414E0AE8Q36175910-36BCEF8E-6325-477D-8660-0DBF1C8406D0Q36271101-25ED7F64-0414-4568-8D1E-BC86DCBF390FQ36584010-A3A8C38B-BFE5-48E8-9401-5E0E7E8B87DDQ37032798-EE846C16-FE41-4E9F-98C8-0FC1BBC7C5C1Q37208181-3DBCC1CE-77F4-4BF5-B787-E7C25CDA67D1Q38017355-4350FC88-006E-4EF7-80B6-4D809021C27CQ38309987-8F7046B2-3602-4707-82E7-041CB3057F04Q39326583-C811BFAB-8B8E-4B96-BAAA-8585392A95D4Q45213293-69A185B6-85E0-48AC-B71A-BFFE30803749
P2860
Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of the Yersi ...... cific small molecule inhibitor
@ast
Crystal structure of the Yersi ...... cific small molecule inhibitor
@en
Crystal structure of the Yersi ...... cific small molecule inhibitor
@nl
type
label
Crystal structure of the Yersi ...... cific small molecule inhibitor
@ast
Crystal structure of the Yersi ...... cific small molecule inhibitor
@en
Crystal structure of the Yersi ...... cific small molecule inhibitor
@nl
prefLabel
Crystal structure of the Yersi ...... cific small molecule inhibitor
@ast
Crystal structure of the Yersi ...... cific small molecule inhibitor
@en
Crystal structure of the Yersi ...... cific small molecule inhibitor
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of the Yersi ...... cific small molecule inhibitor
@en
P2093
Alexander A Fedorov
Jin-Peng Sun
Zhong-Yin Zhang
P2860
P304
P3181
P356
10.1074/JBC.M304693200
P407
P577
2003-08-29T00:00:00Z