Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain - Wikidata - awgldk - TriplyDB

Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain

Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain

http://www.wikidata.org/entity/Q27642070

about

Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein Regulation of Bin1 SH3 domain binding by phosphoinositides Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex The ESCRT complexes: structure and mechanism of a membrane-trafficking network The Vps27/Hse1 Complex Is a GAT Domain-Based Scaffold for Ubiquitin-Dependent Sorting Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes Evolution of domain-peptide interactions to coadapt specificity and affinity to functional diversity Exhaustive search of linear information encoding protein-peptide recognition A lack of peptide binding and decreased thermostability suggests that the CASKIN2 scaffolding protein SH3 domain may be vestigial.The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction A Conserved residue in the yeast Bem1p SH3 domain maintains the high level of binding specificity required for function.The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation.Molecular mechanisms of ubiquitin-dependent membrane traffic Crystallization and preliminary X-ray analysis of the GST-fused human Bri3 N-terminal domain Protein partners of deubiquitinating enzymes.How ubiquitin functions with ESCRTs Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo.The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells.

P2860

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P2860

Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain

http://www.wikidata.org/entity/Q27642070

description

2003 nî lūn-bûn

@nan

2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年学术文章

@wuu

2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

name

Structural insight into modest ...... lecule-2 Src homology 3 domain

@ast

Structural insight into modest ...... lecule-2 Src homology 3 domain

@en

Structural insight into modest ...... lecule-2 Src homology 3 domain

@nl

type

label

Structural insight into modest ...... lecule-2 Src homology 3 domain

@ast

Structural insight into modest ...... lecule-2 Src homology 3 domain

@en

Structural insight into modest ...... lecule-2 Src homology 3 domain

@nl

prefLabel

Structural insight into modest ...... lecule-2 Src homology 3 domain

@ast

Structural insight into modest ...... lecule-2 Src homology 3 domain

@en

Structural insight into modest ...... lecule-2 Src homology 3 domain

@nl

P1433

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P1476

Q27642070-37CB6CEA-D952-4B7C-8A00-24C7C57A0DE2

P2093

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P2860

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P433

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P478

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P50

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P577

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P698

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P3181

P356

P1433

Journal of Biological Chemistry

P1476

Structural insight into modest ...... lecule-2 Src homology 3 domain

@en

P2093

Naomi Kitamura

http://www.w3.org/2001/XMLSchema#string

Nobuo Tanaka

http://www.w3.org/2001/XMLSchema#string

Tadashi Ganbe

http://www.w3.org/2001/XMLSchema#string

Takao Sato

http://www.w3.org/2001/XMLSchema#string

P2860

UBPY: a growth-regulated human ubiquitin isopeptidase.

STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif

SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

Novel recognition mode between Vav and Grb2 SH3 domains

Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.

Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition

Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

P304

48162-48168

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3561489

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P356

10.1074/JBC.M306677200

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P407

P433

48

http://www.w3.org/2001/XMLSchema#string

P478

278

http://www.w3.org/2001/XMLSchema#string

P50

Takashi Kumasaka

Tomonori Kaneko

P577

2003-09-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

13129930

http://www.w3.org/2001/XMLSchema#string