Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes - Wikidata - awgldk - TriplyDB

Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes

Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes

http://www.wikidata.org/entity/Q28511379

about

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome Agonist-promoted Lys63-linked polyubiquitination of the human kappa-opioid receptor is involved in receptor down-regulation Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1 The role of deubiquitinating enzymes in synaptic function and nervous system diseases The ESCRT machinery: from the plasma membrane to endosomes and back again Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases The Deubiquitinating Enzyme UBPY Is Required for Lysosomal Biogenesis and Productive Autophagy in Drosophila Structural Basis for ESCRT-III CHMP3 Recruitment of AMSH Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies.Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)The diabetes susceptibility gene Clec16a regulates mitophagy Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation.Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodies Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7.Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels.Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence.Recent advances in understanding Cushing disease: resistance to glucocorticoid negative feedback and somatic USP8 mutations.Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8.Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized Molecular chaperones, cochaperones, and ubiquitination/deubiquitination system: involvement in the production of high quality spermatozoa.USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation Involvement of lysosomal degradation in VEGF-C-induced down-regulation of VEGFR-3.Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin Endocytosis and intracellular trafficking of ErbBs.The deubiquitinating enzyme USP-46 negatively regulates the degradation of glutamate receptors to control their abundance in the ventral nerve cord of Caenorhabditis elegans.Recurrent gain-of-function USP8 mutations in Cushing's disease.Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis

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Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes

http://www.wikidata.org/entity/Q28511379

description

2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2005

@ast

im November 2005 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2005/11/01)

@sk

vědecký článek publikovaný v roce 2005

@cs

wetenschappelijk artikel (gepubliceerd op 2005/11/01)

@nl

наукова стаття, опублікована в листопаді 2005

@uk

مقالة علمية (نشرت في نوفمبر 2005)

@ar

name

Regulation of epidermal growth ...... deubiquitination at endosomes

@ast

Regulation of epidermal growth ...... deubiquitination at endosomes

@en

Regulation of epidermal growth ...... deubiquitination at endosomes

@nl

type

label

Regulation of epidermal growth ...... deubiquitination at endosomes

@ast

Regulation of epidermal growth ...... deubiquitination at endosomes

@en

Regulation of epidermal growth ...... deubiquitination at endosomes

@nl

prefLabel

Regulation of epidermal growth ...... deubiquitination at endosomes

@ast

Regulation of epidermal growth ...... deubiquitination at endosomes

@en

Regulation of epidermal growth ...... deubiquitination at endosomes

@nl

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MBC.E05-06-0560

P1433

Molecular Biology of the Cell

P1476

Regulation of epidermal growth ...... deubiquitination at endosomes

@en

P2093

Akiko Mukai

http://www.w3.org/2001/XMLSchema#string

Emi Mizuno

http://www.w3.org/2001/XMLSchema#string

Masayuki Komada

http://www.w3.org/2001/XMLSchema#string

Naomi Kitamura

http://www.w3.org/2001/XMLSchema#string

Takanobu Iura

http://www.w3.org/2001/XMLSchema#string

P2860

Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines

ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking

Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor

UBPY: a growth-regulated human ubiquitin isopeptidase.

STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif

P304

5163–5174

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scholarly article

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10.1091/MBC.E05-06-0560

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11

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16

http://www.w3.org/2001/XMLSchema#string

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Tamotsu Yoshimori

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2005-11-01T00:00:00Z

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7639355

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16120644

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P921

Epidermal growth factor receptor

Ubiquitin specific peptidase 8

P932

1266416

http://www.w3.org/2001/XMLSchema#string