An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury
about
Death Associated Protein Kinase 1 (DAPK1): A Regulator of Apoptosis and AutophagyStructural insight into nucleotide recognition by human death-associated protein kinaseHomodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporterDeath-associated protein kinase-mediated cell death modulated by interaction with DANGERFluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor.Targeting protein kinases in central nervous system disordersSite-directed mutagenesis of the glycine-rich loop of death associated protein kinase (DAPK) identifies it as a key structure for catalytic activity.Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesisDeath Associated Protein Kinase (DAPK) -mediated neurodegenerative mechanisms in nematode excitotoxicityDeath-associated protein kinase 1 phosphorylates NDRG2 and induces neuronal cell death.The regulation of smooth muscle contractility by zipper-interacting protein kinase.Genetics of late-onset Alzheimer's disease: progress and prospect.Death associated protein kinases: molecular structure and brain injury.YCl3 Promotes Neuronal Cell Death by Inducing Apoptotic Pathways in Rats.Biochemical and functional characterization of the ROC domain of DAPK establishes a new paradigm of GTP regulation in ROCO proteins.Role of DAPK in neuronal cell death.Kinase inhibitors for CNS diseases: an analysis of the recent patent literature.DAP-kinase and autophagy.Evaluating DAPK as a therapeutic target.DAPK1 Signaling Pathways in Stroke: from Mechanisms to TherapiesAmelioration of oxygen and glucose deprivation-induced neuronal death by chloroform fraction of bay leaves (Laurus nobilis).A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model.Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1.A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cells.A Step-up Approach for Cell Therapy in Stroke: Translational Hurdles of Bone Marrow-Derived Stem Cells.Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits.Death-associated protein kinase is activated by dephosphorylation in response to cerebral ischemia.Synthesis and antibacterial activity of some glucosyl- and ribosyl-pyridazin-3-ones.A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis.Inhibition of death-associated protein kinase 1 attenuates the phosphorylation and amyloidogenic processing of amyloid precursor protein.
P2860
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P2860
An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
An aminopyridazine-based inhib ...... mia induced acute brain injury
@ast
An aminopyridazine-based inhib ...... mia induced acute brain injury
@en
An aminopyridazine-based inhib ...... mia induced acute brain injury
@nl
type
label
An aminopyridazine-based inhib ...... mia induced acute brain injury
@ast
An aminopyridazine-based inhib ...... mia induced acute brain injury
@en
An aminopyridazine-based inhib ...... mia induced acute brain injury
@nl
prefLabel
An aminopyridazine-based inhib ...... mia induced acute brain injury
@ast
An aminopyridazine-based inhib ...... mia induced acute brain injury
@en
An aminopyridazine-based inhib ...... mia induced acute brain injury
@nl
P2093
P3181
P1476
An aminopyridazine-based inhib ...... mia induced acute brain injury
@en
P2093
Anastasia V Velentza
Andrew M Schumacher
Jacques Haiech
Magdalena Zasadzki
Mark S Wainwright
Pamela J Focia
Salida Mirzoeva
P304
P3181
P356
10.1016/S0960-894X(03)00733-9
P407
P577
2003-10-20T00:00:00Z