Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation - Wikidata - awgldk - TriplyDB

Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

http://www.wikidata.org/entity/Q27642340

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The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression IRF7: activation, regulation, modification and function Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity Prevalence and nonrandom distribution of exonic mutations in interferon regulatory factor 6 in 307 families with Van der Woude syndrome and 37 families with popliteal pterygium syndrome Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6 The IRF family, revisited Identification of Caspase-mediated Decay of Interferon Regulatory Factor-3, Exploited by a Kaposi Sarcoma-associated Herpesvirus Immunoregulatory Protein X-ray crystal structure of IRF-3 and its functional implications Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5 The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7 Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation Regulation of the type I IFN induction: a current view Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery Dynamic evolution of immune system regulators: the history of the interferon regulatory factor family In silico mechanistic analysis of IRF3 inactivation and high-risk HPV E6 species-dependent drug response.Structural insights into interferon regulatory factor activation.Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function.Global characterization of interferon regulatory factor (IRF) genes in vertebrates: glimpse of the diversification in evolution.Regulatory serine residues mediate phosphorylation-dependent and phosphorylation-independent activation of interferon regulatory factor 7 Identification of a novel in vivo virus-targeted phosphorylation site in interferon regulatory factor-3 (IRF3)IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.Varicella-zoster virus immediate-early protein 62 blocks interferon regulatory factor 3 (IRF3) phosphorylation at key serine residues: a novel mechanism of IRF3 inhibition among herpesviruses Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling.Mechanisms of autoinhibition of IRF-7 and a probable model for inactivation of IRF-7 by Kaposi's sarcoma-associated herpesvirus protein ORF45 Diversity of interferon antagonist activities mediated by NSP1 proteins of different rotavirus strains.Crosstalk between signaling pathways provided by single and multiple protein phosphorylation sites TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.Innate and adaptive immune responses to herpes simplex virus Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter.Roles of interferon-regulatory factors in T-helper-cell differentiation.Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression Can you hear me now? Regulating transcriptional activators by phosphorylation.Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis

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Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

http://www.wikidata.org/entity/Q27642340

description

2003 nî lūn-bûn

@nan

2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

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2003年論文

@zh-mo

2003年論文

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2003年论文

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name

Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

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Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

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Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

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type

label

Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

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Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

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Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

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prefLabel

Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

@ast

Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

@en

Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

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P356

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Nature structural biology

P1476

Crystal structure of IRF-3 rev ...... irus-induced phosphoactivation

@en

P2093

Bin Y Qin

http://www.w3.org/2001/XMLSchema#string

Cheng Liu

http://www.w3.org/2001/XMLSchema#string

Hema Srinath

http://www.w3.org/2001/XMLSchema#string

John J Correia

http://www.w3.org/2001/XMLSchema#string

Kai Lin

http://www.w3.org/2001/XMLSchema#string

Rachel Delston

http://www.w3.org/2001/XMLSchema#string

Rik Derynck

http://www.w3.org/2001/XMLSchema#string

Suvana S Lam

http://www.w3.org/2001/XMLSchema#string

P2860

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

Structural basis of Smad2 recognition by the Smad anchor for receptor activation

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

Structural basis of Smad1 activation by receptor kinase phosphorylation

Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

P304

913-21

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scholarly article

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1349375

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P356

10.1038/NSB1002

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P433

11

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P478

10

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2003-11-01T00:00:00Z

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5467164

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14555996

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P921

crystal structure