Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target
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Structural characterization of the enzymes composing the arginine deiminase pathway in Mycoplasma penetransStructure-Informed Design of an Enzymatically Inactive Vaccine Component for Group A StreptococcusStructural basis for Ca(2+)-induced activation of human PAD4Born-Oppenheimer ab initio QM/MM molecular dynamics simulations of the hydrolysis reaction catalyzed by protein arginine deiminase 4.Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas.Mechanistic similarity and diversity among the guanidine-modifying members of the pentein superfamily.Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?Impact of manganese, copper and zinc ions on the transcriptome of the nosocomial pathogen Enterococcus faecalis V583.Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli.Role of N-terminal protein formylation in central metabolic processes in Staphylococcus aureus.Ab initio QM/MM free-energy studies of arginine deiminase catalysis: the protonation state of the Cys nucleophileStructure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminaseMechanisms of catalysis and inhibition operative in the arginine deiminase from the human pathogen Giardia lamblia.Protein arginine deiminase 4: evidence for a reverse protonation mechanism.Listeria monocytogenes aguA1, but not aguA2, encodes a functional agmatine deiminase: biochemical characterization of its catalytic properties and roles in acid tolerance.Active site cysteine is protonated in the PAD4 Michaelis complex: evidence from Born-Oppenheimer ab initio QM/MM molecular dynamics simulations.The gene cluster for agmatine catabolism of Enterococcus faecalis: study of recombinant putrescine transcarbamylase and agmatine deiminase and a snapshot of agmatine deiminase catalyzing its reaction.Arginine deiminase: recent advances in discovery, crystal structure, and protein engineering for improved properties as an anti-tumor drug.Directed arginine deiminase evolution for efficient inhibition of arginine-auxotrophic melanomas.Hydrophobic Mutagenesis and Semi-rational Engineering of Arginine Deiminase for Markedly Enhanced Stability and Catalytic Efficiency.Rapid evolution of arginine deiminase for improved anti-tumor activity.Crystal structures representing the Michaelis complex and the thiouronium reaction intermediate of Pseudomonas aeruginosa arginine deiminase.Application of response surface methodology for optimizing arginine deiminase production medium for Enterococcus faecium sp. GR7.Protein engineering of the antitumor enzyme PpADI for improved thermal resistance.
P2860
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P2860
Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structural insight into argini ...... erial and parasite drug target
@ast
Structural insight into argini ...... erial and parasite drug target
@en
Structural insight into argini ...... erial and parasite drug target
@nl
type
label
Structural insight into argini ...... erial and parasite drug target
@ast
Structural insight into argini ...... erial and parasite drug target
@en
Structural insight into argini ...... erial and parasite drug target
@nl
prefLabel
Structural insight into argini ...... erial and parasite drug target
@ast
Structural insight into argini ...... erial and parasite drug target
@en
Structural insight into argini ...... erial and parasite drug target
@nl
P2093
P2860
P356
P1476
Structural insight into argini ...... erial and parasite drug target
@en
P2093
Andrew Howard
Andrey Galkin
Elif Sarikaya
Liudmila Kulakova
P2860
P304
P356
10.1074/JBC.M313410200
P407
P577
2004-04-02T00:00:00Z