Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase
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Structural characterization of the enzymes composing the arginine deiminase pathway in Mycoplasma penetransDeveloping dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxideS-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolaseStructural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug targetPromiscuous Partitioning of a Covalent Intermediate Common in the Pentein SuperfamilyOn the Mechanism of Dimethylarginine Dimethylaminohydrolase Inactivation by 4-HalopyridinesInhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and DevelopmentStructural basis for Ca(2+)-induced activation of human PAD4Zn(II)-free dimethylargininase-1 (DDAH-1) is inhibited upon specific Cys-S-nitrosylationStructural and functional characterization of the Zn(II) site in dimethylargininase-1 (DDAH-1) from bovine brain. Zn(II) release activates DDAH-1.Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysisRetinal metabolic events in preconditioning light stress as revealed by wide-spectrum targeted metabolomics.Mechanistic similarity and diversity among the guanidine-modifying members of the pentein superfamily.Characterisation of the vitreous proteome in proliferative diabetic retinopathy.Crystal structure of N-succinylarginine dihydrolase AstB, bound to substrate and product, an enzyme from the arginine catabolic pathway of Escherichia coli.Polymorphisms in an intronic region of the myocilin gene associated with primary open-angle glaucoma--a possible role for alternate splicing.Discovery of a new class of inhibitors for the protein arginine deiminase type 4 (PAD4) by structure-based virtual screening.Ab initio QM/MM free-energy studies of arginine deiminase catalysis: the protonation state of the Cys nucleophileNitric oxide: therapeutic opportunities.Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivityChemical biology of protein arginine modifications in epigenetic regulationAsymmetric dimethylarginine (ADMA): the silent transition from an 'uraemic toxin' to a global cardiovascular risk molecule.Mechanisms of catalysis and inhibition operative in the arginine deiminase from the human pathogen Giardia lamblia.DDAH gene and cardiovascular risk.ADMA metabolism and clearance.Specific reactions of S-nitrosothiols with cysteine hydrolases: A comparative study between dimethylargininase-1 and CTP synthetase.Protein arginine deiminase 4: evidence for a reverse protonation mechanism.How to control NO production in cells: N(omega),N(omega)-dimethyl-L-arginine dimethylaminohydrolase as a novel drug target.Endogenous inhibitors of nitric oxide and preeclampsia: a review.Intercellular Adhesion Molecule and Endogenous NOS Inhibitor: Asymmetric Dimethylarginine in Pregnant Women with Gestational Diabetes Mellitus.Determination of the diagnostic values of asymmetric dimethylarginine as an indicator for evaluation of the endothelial dysfunction in patients with rheumatoid arthritisUnexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.Ligand-dependent dynamics of the active-site lid in bacterial dimethylarginine dimethylaminohydrolase.Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?Role of asymmetrical dimethylarginine in the progression of renal disease.The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis.The endothelial ADMA/NO pathway in hypoxia-related chronic respiratory diseases.Arginine deiminase: recent advances in discovery, crystal structure, and protein engineering for improved properties as an anti-tumor drug.Genetic variations in the alanine-glyoxylate aminotransferase 2 (AGXT2) gene and dimethylarginines levels in rheumatoid arthritis.DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
P2860
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P2860
Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structural insights into the h ...... rginine dimethylaminohydrolase
@ast
Structural insights into the h ...... rginine dimethylaminohydrolase
@en
Structural insights into the h ...... rginine dimethylaminohydrolase
@nl
type
label
Structural insights into the h ...... rginine dimethylaminohydrolase
@ast
Structural insights into the h ...... rginine dimethylaminohydrolase
@en
Structural insights into the h ...... rginine dimethylaminohydrolase
@nl
prefLabel
Structural insights into the h ...... rginine dimethylaminohydrolase
@ast
Structural insights into the h ...... rginine dimethylaminohydrolase
@en
Structural insights into the h ...... rginine dimethylaminohydrolase
@nl
P2093
P356
P1476
Structural insights into the h ...... rginine dimethylaminohydrolase
@en
P2093
McAlister M
McDonald N
Murray-Rust J
Santa Maria J
Vallance P
P304
P356
10.1038/90387
P577
2001-08-01T00:00:00Z