Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution

Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution

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http://www.wikidata.org/entity/Q27642916
Structural Basis for Recognition of Urokinase-type Plasminogen Activator by Plasminogen Activator Inhibitor-1CSAR benchmark exercise 2011-2012: evaluation of results from docking and relative ranking of blinded congeneric seriesDocking challenge: protein sampling and molecular docking performance.A urokinase-type plasminogen activator-inhibiting cyclic peptide with an unusual P2 residue and an extended protease binding surface demonstrates new modalities for enzyme inhibition.Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator.Hit clustering can improve virtual fragment screening: CDK2 and PARP1 case studies.Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptorsNew Frontiers in Druggability2-Amidino analogs of glycine-amiloride conjugates: inhibitors of urokinase-type plasminogen activator.A potent and highly efficacious Bcl-2/Bcl-xL inhibitor.Comparative binding energy analysis for binding affinity and target selectivity prediction.Prediction of Positions of Active Compounds Makes It Possible To Increase Activity in Fragment-Based Drug Development.Challenging the gold standard for 3D-QSAR: template CoMFA versus X-ray alignment.Development of antitrypanosomal and antiplasmodial nonpeptidic cysteine protease inhibitors based on N-protected-guanidino-furan and -pyrrole building blocks.Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.Lithium Hexamethyldisilazane Transformation of Transiently Protected 4-Aza/Benzimidazole Nitriles to Amidines and their Dimethyl Sulfoxide Mediated Imidazole Ring Formation.
P2860

Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution

Item
http://www.wikidata.org/entity/Q27642916
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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name
Identification of novel bindin ...... N-phenyl amide 6-substitution
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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type
label
Identification of novel bindin ...... N-phenyl amide 6-substitution
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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P2093
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Identification of novel bindin ...... N-phenyl amide 6-substitution
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P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698