Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants

Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants

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http://www.wikidata.org/entity/Q27643376
Q27640864
sameAs
High-resolution crystal structures of factor XIa coagulation factor in complex with nonbasic high-affinity synthetic inhibitorsCreating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug designDesigning allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides.Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIaDiscovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site.Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitorsComprehensive Analysis of Structure-Activity Relationships of α-Ketoheterocycles as sn-1-Diacylglycerol Lipase α InhibitorsPF-04886847 (an inhibitor of plasma kallikrein) attenuates inflammatory mediators and activation of blood coagulation in rat model of lipopolysaccharide (LPS)-induced sepsisFactor XIa inhibitors: A review of the patent literature.Coagulation factor XI as a novel target for antithrombotic treatment.The many faces of the contact pathway and their role in thrombosis.Factor XI and XII as antithrombotic targets.Design and evaluation of Trypanosoma brucei metacaspase inhibitors.Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer.A novel approach in potential anticoagulants from peptides epitope 558-565 of A2 subunit of factor VIII.Curcumin inhibits hepatocellular carcinoma growth by targeting VEGF expression.
P2860

Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants

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http://www.wikidata.org/entity/Q27643376
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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type
label
Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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prefLabel
Design, synthesis, and biologi ...... or XIa as novel anticoagulants
@ast
Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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P1476
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Design, synthesis, and biologi ...... or XIa as novel anticoagulants
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P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921