Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex
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The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutationsCaspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loopStructure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity responseThe enigma of caspase-2: the laymen's viewThe structural biology of Toll-like receptorsCutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytesCrystallization and preliminary X-ray crystallographic studies of the oligomeric death-domain complex between PIDD and RAIDDPrion-like polymerization as a signaling mechanismThe PIDDosome, DNA-damage-induced apoptosis and beyondHelical assembly in the death domain (DD) superfamilyMolecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domainHelical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signallingStructural and Functional Analysis of the NLRP4 Pyrin DomainCrystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome AssemblyStructure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I ActivationChanges in Apaf-1 Conformation That Drive Apoptosome AssemblyStructure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome AssemblyMDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNAStructure of the caspase-recruitment domain from a zebrafish guanylate-binding proteinStructural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly.The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidizedStructural basis for ubiquitin-mediated antiviral signal activation by RIG-IDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseMyD88: a central player in innate immune signalingDNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenanceStructural mechanisms of inflammasome assemblyThe nucleic acid-sensing inflammasomesMapping of POP1-binding site on pyrin domain of ASCGenetic mapping and exome sequencing identify variants associated with five novel diseasesStructural characterization of the self-association of the death domain of p75(NTR.)Inflammatory cells regulate p53 and caspases in acute pancreatitisEngagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transductionCryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.Structural features of caspase-activating complexesMDA5 assembles into a polar helical filament on dsRNA.Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly.Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells
P2860
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P2860
Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@ast
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@en
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@nl
type
label
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@ast
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@en
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@nl
prefLabel
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@ast
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@en
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@nl
P2093
P2860
P3181
P1433
P1476
Death Domain Assembly Mechanis ...... gomeric PIDDosome Core Complex
@en
P2093
Emmanuelle Logette
Hyun Ho Park
Solange Cuenin
Thomas Walz
P2860
P304
P3181
P356
10.1016/J.CELL.2007.01.019
P407
P577
2007-02-09T00:00:00Z