Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases
about
The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevisCullin-RING ubiquitin ligases: global regulation and activation cyclesStructural basis of selective ubiquitination of TRF1 by SCFFbx4Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligaseThe stomatin-like protein SLP-1 and Cdk2 interact with the F-Box protein Fbw7-γThe glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitorStructural basis for recruitment of BRCA2 by PALB2Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substratesMicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7Identification, analysis, and prediction of protein ubiquitination sitesCascades of multisite phosphorylation control Sic1 destruction at the onset of S phaseDiversity of degradation signals in the ubiquitin-proteasome systemA promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machineryFbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradationJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Short linear motifs - ex nihilo evolution of protein regulationProtein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processesFBW7-mediated ubiquitination and degradation of KLF5Building and remodelling Cullin-RING E3 ubiquitin ligasesFunctional diversity and structural disorder in the human ubiquitination pathwayStructure of the SOCS4-ElonginB/C Complex Reveals a Distinct SOCS Box Interface and the Molecular Basis for SOCS-Dependent EGFR DegradationE2 interaction and dimerization in the crystal structure of TRAF6Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin LigasesAn allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligaseA Dual E3 Mechanism for Rub1 Ligation to Cdc53WD40 Repeat Propellers Define a Ubiquitin-Binding Domain that Regulates Turnover of F Box ProteinsStructure and function of WD40 domain proteinsStructural Basis of Outer Membrane Protein Biogenesis in BacteriaStructure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceComposite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligaseBub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signalingCRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencingStructure of the FP domain of Fbxo7 reveals a novel mode of protein-protein interactionThe FP domains of PI31 and Fbxo7 have the same protein fold but very different modes of protein-protein interactionCdk1-dependent destruction of Eco1 prevents cohesion establishment after S phase
P2860
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P2860
Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@ast
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@en
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@nl
type
label
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@ast
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@en
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@nl
prefLabel
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@ast
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@en
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@nl
P2093
P921
P3181
P1433
P1476
Structure of a Fbw7-Skp1-cycli ...... ition by SCF ubiquitin ligases
@en
P2093
Mathew E Sowa
Nikola P Pavletich
Stephanie Oehlmann
P304
P3181
P356
10.1016/J.MOLCEL.2007.02.022
P577
2007-04-01T00:00:00Z