Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
about
Structures of the bacterial ribosome in classical and hybrid states of tRNA bindingMutational analysis of S12 protein and implications for the accuracy of decoding by the ribosometRNAs as antibiotic targetsA brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruitsStructural basis for protein synthesis: snapshots of the ribosome in motionAntibiotics that target protein synthesisAntiviral activity of geneticin against dengue virus.A Steric Block in Translation Caused by the Antibiotic SpectinomycinSpecific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into SubunitsStructural basis for hygromycin B inhibition of protein biosynthesisCrystal structure of a translation termination complex formed with release factor RF2The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosomeAllosteric control of the ribosome by small-molecule antibiotics.Crystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNAA structural basis for streptomycin-induced misreading of the genetic codeThe Impact of Aminoglycosides on the Dynamics of Translation ElongationA dynamic structural model of expanded RNA CAG repeats: a refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations.Structural insights into initial and intermediate steps of the ribosome-recycling process.Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ4′-O-substitutions determine selectivity of aminoglycoside antibioticsCrystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sitesThe antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocationRibosome. The complete structure of the 55S mammalian mitochondrial ribosomeHflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditionsTargeting Antibiotic ResistanceMembrane proteases and aminoglycoside antibiotic resistanceImprints of the genetic code in the ribosomeApproaches to Validate and Manipulate RNA Targets with Small Molecules in CellsMagnesium-binding architectures in RNA crystal structures: validation, binding preferences, classification and motif detection.Interplay of the bacterial ribosomal A-site, S12 protein mutations and paromomycin binding: a molecular dynamics study.A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity.Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.The process of mRNA-tRNA translocationAminoglycoside activity observed on single pre-translocation ribosome complexes.Structure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity.tRNA mimicry in translation termination and beyond.Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside-RNA hairpin loop interactionsTwo-dimensional combinatorial screening of a bacterial rRNA A-site-like motif library: defining privileged asymmetric internal loops that bind aminoglycosides.Ribosomal protein S12 and aminoglycoside antibiotics modulate A-site mRNA cleavage and transfer-messenger RNA activity in Escherichia coliTobramycin at subinhibitory concentration inhibits the RhlI/R quorum sensing system in a Pseudomonas aeruginosa environmental isolate
P2860
Q24635922-D6E2CFFB-BD44-4F2A-ABDE-E984F1903BB6Q24651010-641FF74B-965D-48DC-AAF6-D6460E62399EQ26822430-075785B4-F5FE-45F1-8CAE-18EDF4CBFD94Q26823889-65783BBC-7665-4524-A139-53A6A5424D18Q27022034-0E4535F7-BC3E-4ED8-9A74-9C603805E9F8Q27025271-1BCD80D6-8088-4CBF-920A-26D18A224271Q27488716-CFCAAC01-0EC2-4526-969A-5B95A7C75B8DQ27647153-4040045C-2634-4E43-9828-03D82A81F4FDQ27648998-A5F61407-AB16-420B-9663-14E97207A59EQ27650910-D337B59D-7DA5-462A-8910-264FD6F41348Q27653093-08175FA8-5E17-4CA7-B209-24B746C678EFQ27659850-47564192-34A5-4CF2-B76D-8946C2387B78Q27671570-71611AA0-19F6-4FF9-80F5-84268CA1A139Q27671703-59F09C44-B078-4D89-A596-943A988D69D0Q27675910-E36A8DC9-1D07-48EF-8B4B-292D25E7A399Q27676402-749B55C0-3700-493E-9CDA-5625DA4728FFQ27676633-C9D69E14-EC94-4241-A4A5-CA69FBC1E752Q27677822-07595B6C-399B-43DF-A641-24366AFC7014Q27679679-5ECC54A3-4DD6-4BBE-AD02-DA414647C191Q27681495-A7371236-345D-4B32-8D8C-9C85A9C1913FQ27684075-95A2D7E8-F494-41D0-B5E1-0D7065AAD4F8Q27688875-A7129437-BF1C-4C94-B768-D9C428FA7805Q27700074-1008D16F-3B2B-43AB-B684-2BE3F10E46C7Q27702284-D1349F42-9C54-44C0-A33B-22632CA8B11DQ28078130-762150A2-3783-4A0C-A821-D890D08349CDQ28492797-A6D521B3-55B9-43CB-9529-36A477B5EE2EQ28751318-54887968-7C67-469B-BA75-589DFE3B9FF0Q28833658-9F3FCD0D-CA07-45B4-ACE3-B69931B153BCQ30300321-F37F7E7A-12B0-4021-B201-1446EB6501EDQ30301316-37E80D70-D5B3-47A8-8EA7-4F9C0BAD88A5Q30417680-3E28D67E-1CC3-46FF-B313-D920EBA641B8Q30474223-D19CEFBC-76EC-4379-9611-FD2A46433AF8Q30480890-3CE0D21E-B8E9-449B-8E2F-89F2D32F7938Q30495847-EDCB418B-730B-4116-A667-05E310A87A06Q30573524-31C5BE3A-7B03-4759-A151-C088FC1B9709Q33351954-3870B5FB-07CB-44ED-9FA9-BCA1E04296E7Q33499621-6D31B11E-5568-4DE9-A237-7C9DCD5F4C01Q33527092-960BFD35-685C-4D4D-B5D0-BA9709A59302Q33553894-7DE0246D-0F56-4CBE-B82F-426669BD90C6Q33594902-3699404D-C796-4FD4-8EFA-9C1CECB7139C
P2860
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@ast
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@en
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@nl
type
label
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@ast
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@en
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@nl
prefLabel
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@ast
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@en
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@nl
P2093
P2860
P3181
P356
P1476
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
@en
P2093
Akira Kaji
Barbara S Schuwirth
Go Hirokawa
Hideko Kaji
James M Holton
Jamie H Doudna Cate
Maria A Borovinskaya
P2860
P2888
P304
P3181
P356
10.1038/NSMB1271
P577
2007-08-01T00:00:00Z
P5875
P6179
1019882979